Protein Info for Psest_0392 in Pseudomonas stutzeri RCH2

Annotation: Signal transduction histidine kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1169 transmembrane" amino acids 20 to 41 (22 residues), see Phobius details amino acids 181 to 204 (24 residues), see Phobius details PF05227: CHASE3" amino acids 45 to 177 (133 residues), 107.7 bits, see alignment E=1.6e-34 PF13185: GAF_2" amino acids 253 to 386 (134 residues), 60.5 bits, see alignment E=7.6e-20 PF01590: GAF" amino acids 258 to 385 (128 residues), 37.4 bits, see alignment E=1.2e-12 PF00512: HisKA" amino acids 492 to 559 (68 residues), 64.2 bits, see alignment 3.3e-21 PF02518: HATPase_c" amino acids 607 to 716 (110 residues), 102.2 bits, see alignment E=8.1e-33 PF00072: Response_reg" amino acids 779 to 885 (107 residues), 65.3 bits, see alignment E=1.9e-21 amino acids 901 to 1010 (110 residues), 63.9 bits, see alignment E=5.2e-21 amino acids 1047 to 1159 (113 residues), 96.4 bits, see alignment E=4.2e-31

Best Hits

KEGG orthology group: None (inferred from 91% identity to psa:PST_3885)

Predicted SEED Role

"Signal transduction histidine kinase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0GE57 at UniProt or InterPro

Protein Sequence (1169 amino acids)

>Psest_0392 Signal transduction histidine kinase (Pseudomonas stutzeri RCH2)
MSESFIDQSNFRRILNRNVAVPLGFGFLSAFFFSAIVYYLLSVGHWVEQSVKGVAHAHEA
LRLVADLETGLRGYLIAGEEPFLDPYRQGLGQMERELDALKVYAGSDPLQLSRLEKIDAA
HHLWLAFAEEGISRRAAGEPVVDYVRTRRGLDLTNQRRNLLNEFIAEERQLRAQRTDTSE
VITTALIGGFLLFSLIFSGMLVYLGRRDLTSLSTTYSELLGKQHAHAEALEQQAWYRTGQ
TQLSDSIIGELALPALGQGVLNFLSRYIDAAVGALYVVQDGKLQRVAEYAYDPDHLQSGR
TLNVGTGLVGQAALERRVMALEDLPADYLKVTSALGDTAPRSVLIVPVEDSGMLNGVIEL
GFLRPLREQDSELLRRIAPSIASAIEAARYRQRLQKVLAETQQLNEELQVQQEELRAANE
ELEEQSNALRESQAHMEEQQAELEQTNEQLAEQTEALARQRDQMDEKNQRLNEAQLMLEQ
RADELQRASRYKSEFLANMSHELRTPLNSSLILAKLLADNPAGNLSDEQVQFARSIYSAG
NDLLTLINDILDISKVEAGKFEVHPELTILSRLVDGMKNLFLPQAMERSLQFSVELADDL
PASLFTDRQRLEQILKNLLANAFKFTEKGSVTLRVEPRDDDLLAFAVRDTGIGIAQEQQA
VIFEAFRQADGTTNRRYGGTGLGLSISRELANLLGGQIEVQSAPGAGSTFTLVVPQSYSE
ARVAEPLVVEPSSSPSLPSRPVEPPQRRAEPQAPRHAVSAPPQRLPDDRDRFPFKERCVL
VIEDEPQFARILHDLAHELQYSCLLAQNADDGFDTALQYKPDAILLDMRLPDHSGLTVLE
RLKENPATRHIPVHVVSVEDRKEAAMQMGAVGYAMKPTTREELKDVFSRLEAKLAQKVKR
ILLVEDDALQRESMSRLIEDVDIEITAVEFGAQALEQLRDTVFDCMIIDLKLPDMDGSEL
LERMAKEDICSFPPVIVYTGRNLTRDEEAALLKYSRSIIIKGARSPERLLDEVTLFLHKV
ESDMPPERQKMLKSARSREKAFEGRKILVVDDDVRNVFALTSALEQKGALVEIARNGLEA
IDKLQHDTDIDLVLMDIMMPEMDGFTAMQEIRKDVRFAKLPIIAVTAKAMKDDQDRCLSA
GANDYLAKPIDLDRLFSLIRVWLPKVELL