Protein Info for HP15_3848 in Marinobacter adhaerens HP15

Annotation: RNA polymerase, sigma-24 subunit, ECF subfamily

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 205 TIGR02937: RNA polymerase sigma factor, sigma-70 family" amino acids 23 to 192 (170 residues), 73 bits, see alignment E=1.1e-24 PF04542: Sigma70_r2" amino acids 28 to 93 (66 residues), 51.5 bits, see alignment E=7.1e-18 PF08281: Sigma70_r4_2" amino acids 140 to 192 (53 residues), 39.1 bits, see alignment E=4.8e-14

Best Hits

KEGG orthology group: K03088, RNA polymerase sigma-70 factor, ECF subfamily (inferred from 34% identity to scl:sce0695)

Predicted SEED Role

"probable sigma-70 factor, ECF subfamily protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See E4PJ14 at UniProt or InterPro

Protein Sequence (205 amino acids)

>HP15_3848 RNA polymerase, sigma-24 subunit, ECF subfamily (Marinobacter adhaerens HP15)
MTDSSREKEIELIQGLKTGDNDSFQEAVRAYTPGMLAVARFYLDHSSAEEAVQDCWVKVI
DAIHGFEGRSGLKTWLHRVVANRCKNQLRSAKREVSSDFSEALEPALSDRFNAKGRWELP
PKLQFHDSADTLMENGALSDCLDKHLSALPETQRSALMLYEAHQHKSDDVCNILDVSASN
LRVLLHRARQKIFLMVENFQETGEC