Protein Info for PGA1_78p00090 in Phaeobacter inhibens DSM 17395

Annotation: putative HTH-type transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 149 signal peptide" amino acids 1 to 22 (22 residues), see Phobius details TIGR00738: Rrf2 family protein" amino acids 1 to 126 (126 residues), 99.2 bits, see alignment E=8.5e-33 PF02082: Rrf2" amino acids 5 to 127 (123 residues), 105.6 bits, see alignment E=2.3e-34 PF09339: HTH_IclR" amino acids 10 to 55 (46 residues), 22.3 bits, see alignment E=9.3e-09

Best Hits

Swiss-Prot: 35% identical to NSRR_SERP5: HTH-type transcriptional repressor NsrR (nsrR) from Serratia proteamaculans (strain 568)

KEGG orthology group: K13771, Rrf2 family transcriptional regulator, nitric oxide-sensitive transcriptional repressor (inferred from 42% identity to pva:Pvag_2786)

Predicted SEED Role

"Nitrite-sensitive transcriptional repressor NsrR" in subsystem Nitrosative stress or Oxidative stress or Rrf2 family transcriptional regulators

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See I7F4X9 at UniProt or InterPro

Protein Sequence (149 amino acids)

>PGA1_78p00090 putative HTH-type transcriptional regulator (Phaeobacter inhibens DSM 17395)
MKLNLKTDYALRLLILLATRPEQQFEIETLSRIHQLPASSVMKIISELVRHGYVHSIRGR
SGGVQIGRKPSEIRVGDIVHAMNEPMEIVDCSSCLLVGNCRLKGVLCEAAQAFTEVLMAY
RLSDLIEAPAPVLTPLLDRDNGADPTSQT