Protein Info for HP15_3782 in Marinobacter adhaerens HP15

Annotation: RNA helicase, ATP-dependent DEAH box, HrpB type

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 826 TIGR01970: ATP-dependent helicase HrpB" amino acids 2 to 823 (822 residues), 1077.5 bits, see alignment E=0 PF00270: DEAD" amino acids 17 to 159 (143 residues), 34.8 bits, see alignment E=2.1e-12 PF00271: Helicase_C" amino acids 204 to 326 (123 residues), 49.2 bits, see alignment E=8.6e-17 PF08482: HrpB_C" amino acids 679 to 811 (133 residues), 183 bits, see alignment E=4.9e-58

Best Hits

KEGG orthology group: K03579, ATP-dependent helicase HrpB [EC: 3.6.4.13] (inferred from 78% identity to maq:Maqu_0073)

Predicted SEED Role

"ATP-dependent helicase HrpB"

Isozymes

Compare fitness of predicted isozymes for: 3.6.4.13

Use Curated BLAST to search for 3.6.4.13

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See E4PI60 at UniProt or InterPro

Protein Sequence (826 amino acids)

>HP15_3782 RNA helicase, ATP-dependent DEAH box, HrpB type (Marinobacter adhaerens HP15)
MLPIDAILPDLKAALERTTTVLLQAPPGAGKTTRVPAALLDAPWRGDGKILMLEPRRLAA
RSAARFMARQLNEQPGQTVGYRTRLDTRVSAATRIEVVTEGILTRLIQADPMLEEYAAVI
FDEFHERSLQADLGLALVRESQQALREDLRLLVMSATLDTGPIAQVLGDVPVITSEGRAF
PVDVHYRPLPRSGRMVDQVTAVVREALAEQSGSLLVFLPGVGEIRRVEQQLRANLPDRVM
LAPLYGNLKSEQQDQAISPAPEGQRKVVLATAIAETSLTIEGVRVVIDCGQQRRAVFDPN
SGMTRLVTGRVSRASAEQRKGRAGRMEPGVCYRLWSESEQFGLADYTPPEILEADLAPLV
LELAQWGAREADAVAWIDKPPAAHWRQAVALLQWLDLLDSDGAITDHGKAARELGIHPRL
AHMVLKGRSIGLGGAAAAVAALLEERDLLGPGTGADMHERVRVFFGERRDRTLDVARLKA
VRQSARRLSGPGATEATPPTETEIGRLLALAYPDRIARRRSDKAARYQLSNGKGAVLRED
DPLARHEWLVAAELDGQAREATIYLAAPVDIPDLELDLADHIKEIEEALWDDSQGKILAR
RARKLGELVLEEKPLGRVDPELVRQGLLSAIRKKGLESLPWSDGSRQWRARLRLLARTFP
DSGWPDTDDAALLDNLEVWLGPFLVGMTRWSDLARIDLLAALNSLIDYPAQQQLQSLAPT
HLTIPTGQRVSLDYTADNGPVLAAKLQALFGWKETPAVAGGRVPVVLHLLSPAQRPLAVT
ADLAGFWRNAYPEVRKDMRGRYPKHPWPEDPFTAEAQQGTKKRPTR