Protein Info for PGA1_262p02110 in Phaeobacter inhibens DSM 17395

Annotation: putative chemotaxis protein CheW

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 162 PF01584: CheW" amino acids 21 to 155 (135 residues), 131.8 bits, see alignment E=6.8e-43

Best Hits

Swiss-Prot: 43% identical to CHEW_RHOSH: Chemotaxis protein CheW (cheW) from Rhodobacter sphaeroides

KEGG orthology group: K03408, purine-binding chemotaxis protein CheW (inferred from 89% identity to sit:TM1040_3205)

Predicted SEED Role

"Positive regulator of CheA protein activity (CheW)" in subsystem Bacterial Chemotaxis or Two-component regulatory systems in Campylobacter

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See I7F2K5 at UniProt or InterPro

Protein Sequence (162 amino acids)

>PGA1_262p02110 putative chemotaxis protein CheW (Phaeobacter inhibens DSM 17395)
MQSQAEAKYDDSEIKHAQHSEFVSFTVAGQAFCLKITQIREIRRWSPVTILPHAPADVLG
VMNLRGAVIPIYDLSARFGLQQTEASERNVVIVVSVHGKPVGLLAESVSEIISINPDDIQ
DTPPVDSRNTMDYIQGIISHDETMVRIINLDAVITVPEQVIS