Protein Info for Psest_3847 in Pseudomonas stutzeri RCH2

Annotation: Hemolysins and related proteins containing CBS domains

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 447 transmembrane" amino acids 12 to 35 (24 residues), see Phobius details amino acids 70 to 90 (21 residues), see Phobius details amino acids 110 to 135 (26 residues), see Phobius details amino acids 148 to 170 (23 residues), see Phobius details PF01595: CNNM" amino acids 21 to 208 (188 residues), 174.1 bits, see alignment E=3.6e-55 PF00571: CBS" amino acids 238 to 288 (51 residues), 37.6 bits, see alignment 3.5e-13 amino acids 304 to 353 (50 residues), 24 bits, see alignment 6.3e-09 PF03471: CorC_HlyC" amino acids 372 to 442 (71 residues), 56.2 bits, see alignment E=4.4e-19

Best Hits

KEGG orthology group: None (inferred from 99% identity to psa:PST_0425)

Predicted SEED Role

"Magnesium and cobalt efflux protein CorC" in subsystem Copper homeostasis: copper tolerance or Phosphate metabolism

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0GRA0 at UniProt or InterPro

Protein Sequence (447 amino acids)

>Psest_3847 Hemolysins and related proteins containing CBS domains (Pseudomonas stutzeri RCH2)
MDPSPSYAASSYFADFGLILFALFLVLLNGFFVAAEFAMVKLRATKVEAIASRHGWRGHI
LRTVHNQLDAYLSACQLGITLASLGLGWVGEPAFAHLLEPLLAGIGIQSPALVHGIAFFT
AFFIISYLHIVIGELAPKSWAIRKPELLSLWTAVPLYLFYWLMYPAIYLLNASANAILRI
AGQGEPGMHHDHHYSREELKLILHSNRARDPSNPQIQVLASAVEMSELEVVDWANSREDL
LQLEHDAPLAEILEIIRRHKYSRYPVYDSAKGEYVGLLHIKDLLLALAANGALAEDFCLG
ELLRPLERVSKHMPLASLLEQFRQGGAHFVLVEEGDHKVIGFLTMEDVLEVLVGDIQDEH
RKTERGVLAYQPGKLLVRGDTPLFKLERLLGIDLDHVEAETLAGLVYETLKRVPDENEVL
QVDGLQIVIKKMRGPKIVLAKVLLFKD