Protein Info for PGA1_262p01710 in Phaeobacter inhibens DSM 17395

Annotation: putative glutathione transport system permease protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 312 signal peptide" amino acids 1 to 30 (30 residues), see Phobius details transmembrane" amino acids 101 to 122 (22 residues), see Phobius details amino acids 134 to 159 (26 residues), see Phobius details amino acids 178 to 197 (20 residues), see Phobius details amino acids 228 to 254 (27 residues), see Phobius details amino acids 278 to 302 (25 residues), see Phobius details PF19300: BPD_transp_1_N" amino acids 1 to 75 (75 residues), 39.5 bits, see alignment E=5.7e-14 PF00528: BPD_transp_1" amino acids 113 to 309 (197 residues), 114.7 bits, see alignment E=4.4e-37

Best Hits

Swiss-Prot: 37% identical to GSIC_SALTI: Glutathione transport system permease protein GsiC (gsiC) from Salmonella typhi

KEGG orthology group: K02033, peptide/nickel transport system permease protein (inferred from 70% identity to sil:SPO2834)

MetaCyc: 34% identical to glutathione ABC transporter membrane subunit GsiC (Escherichia coli K-12 substr. MG1655)
RXN0-11 [EC: 7.4.2.10]

Predicted SEED Role

"Dipeptide transport system permease protein DppB (TC 3.A.1.5.2)" in subsystem ABC transporter dipeptide (TC 3.A.1.5.2) (TC 3.A.1.5.2)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.4.2.10

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See I7F2H3 at UniProt or InterPro

Protein Sequence (312 amino acids)

>PGA1_262p01710 putative glutathione transport system permease protein (Phaeobacter inhibens DSM 17395)
MIQFTLKRFALAALILVVAVTVMFLMIRAVPGDPVSIMLGPRATPELKARLIAEMALDQS
IPKQLLIYFGGLLRGDLGVDVFSGRAVTTIVFEQLPHTLKLIFSAITWSALLGIGIGCYA
AAHPNTWIDRAAATLSVSFIAAPAFVVALLSLLVFAVYLQWFPAIGVGDGFWDQVHHLVL
PSLAIGLSWVGYIARLVRASMLEVMGESHIRTARAFGLSERRIVGIYALRIAILPVVTVI
GVGMGFLLSSAVFTEIVFARPGLGKLVIDSITTRNYPIVMGAVLVSTALFVISTALADLI
NAILDPRARSNT