Protein Info for HP15_3699 in Marinobacter adhaerens HP15

Annotation: inner membrane protein translocase component YidC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 571 transmembrane" amino acids 6 to 23 (18 residues), see Phobius details amino acids 358 to 376 (19 residues), see Phobius details amino acids 382 to 402 (21 residues), see Phobius details amino acids 446 to 468 (23 residues), see Phobius details amino acids 488 to 506 (19 residues), see Phobius details amino acids 526 to 546 (21 residues), see Phobius details TIGR03593: membrane protein insertase, YidC/Oxa1 family, N-terminal domain" amino acids 4 to 380 (377 residues), 356.5 bits, see alignment E=2.3e-110 PF14849: YidC_periplas" amino acids 94 to 370 (277 residues), 280.2 bits, see alignment E=2.9e-87 TIGR03592: membrane protein insertase, YidC/Oxa1 family" amino acids 381 to 560 (180 residues), 233.4 bits, see alignment E=2.2e-73 PF02096: 60KD_IMP" amino acids 382 to 560 (179 residues), 215.3 bits, see alignment E=5e-68

Best Hits

Swiss-Prot: 77% identical to YIDC_MARHV: Membrane protein insertase YidC (yidC) from Marinobacter hydrocarbonoclasticus (strain ATCC 700491 / DSM 11845 / VT8)

KEGG orthology group: K03217, preprotein translocase subunit YidC (inferred from 77% identity to maq:Maqu_3895)

Predicted SEED Role

"Inner membrane protein translocase component YidC, long form"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See E4PHG2 at UniProt or InterPro

Protein Sequence (571 amino acids)

>HP15_3699 inner membrane protein translocase component YidC (Marinobacter adhaerens HP15)
MDIQRIVLFAGLAIVSYLMVLAWNEDYHQPPETAQVAESQPSQTAGNMGNSDNMVLPEDS
SAQVDGDGEFTTPETGQAVISSTETTTAVSDQFITVRTDVYDLQIDRVSGNLVKARLLDY
DDTLNSEKPLTLLNNTQNRLYVLESGLIGRDGPDSRKNGSAPVYSADAASYELAEGDNQL
QVDLTYTSDNGVQITKRYEFERNSYEISVKYLVENQSSEEWQANFTGKIVRDQSPDPTSQ
TSMGIQAFLGLVISSPEDPYEKFDFGDLQENQINQSVTNGWLAFLQHYFLSAWVPERDIP
AQYQTTRRGPNYVMGFVYPATSVAPGETAEIGARAYVGPKIIERLEGMAPNLDRTVDFGW
LFFISLPLFIILDWFHSLVGNWGVSIILLTVLVKAVFFHLSATSYKSMAKMRAVAPQLTR
LKELYGDDRQRMSQEMMALYKREKINPLGGCLPILVQMPVFISLYWVLFESVQLRHAPFM
LWIQDLSVMDPYFILPILMGASMFLQMSLNPTPPDPMQAKIMKMMPLIFTVFFLWFPAGL
VLYWLVNNILSIAQQWYITRKIEAEMAGKKH