Protein Info for PGA1_262p01530 in Phaeobacter inhibens DSM 17395

Annotation: transcriptional regulator, GntR family

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 489 signal peptide" amino acids 1 to 21 (21 residues), see Phobius details transmembrane" amino acids 322 to 343 (22 residues), see Phobius details PF00392: GntR" amino acids 24 to 86 (63 residues), 52.9 bits, see alignment E=2.4e-18 PF00155: Aminotran_1_2" amino acids 164 to 481 (318 residues), 73.3 bits, see alignment E=2.3e-24

Best Hits

Predicted SEED Role

"Predicted transcriptional regulator of pyridoxine metabolism" in subsystem Pyridoxin (Vitamin B6) Biosynthesis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See I7E6E8 at UniProt or InterPro

Protein Sequence (489 amino acids)

>PGA1_262p01530 transcriptional regulator, GntR family (Phaeobacter inhibens DSM 17395)
MAKTRTGAALLSLSLDRDGADTLQAQLLAQLRRLILDRMISPGSKLPSSRTLAEELSVSR
VTVSAVIDQLISEGYLEGRARSGVYVEAELPDQLPEAQSGTAASMEQGRSGTFPEEASPA
VPATLRPFDASAPELTLFPYRQWARHHDQTWRRPDAALLSRVDSFGWPPLREAIADHLRE
WRGLPCTAEQIFITSGVVEAISLIAAATLNEGDVVLTEEPGYAVLNRAVHQNRLIPVPSP
VDQQGFDIKTALQTAPRAKAAIVTPSRHYPLGVTLPLSRRLELIEWAVGCNAYVIEDDFD
SEYRFQGKPLPAMMSLSNQDRVIYVGSFSKVIFSAMRLGFVVFPKSMLPKVRSALSQTDQ
QASLMLQPVLARFMQSGDFAIHIRRMRRLYAKRQAAVLKAIKLHAADLLIVDPVPAGMHL
VAMLTPDLQNRMNDTEAAERAKSAGVIVQPLSSFFAGPPVNQGLVMGFAGFSEERLEKGV
QDLAAALRV