Protein Info for PGA1_262p01360 in Phaeobacter inhibens DSM 17395

Annotation: transcriptional regulator, LysR family

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 313 PF00126: HTH_1" amino acids 24 to 82 (59 residues), 73.1 bits, see alignment E=1.4e-24 PF03466: LysR_substrate" amino acids 107 to 307 (201 residues), 108.1 bits, see alignment E=4.3e-35

Best Hits

KEGG orthology group: None (inferred from 59% identity to sit:TM1040_2058)

Predicted SEED Role

"Glycine cleavage system transcriptional activator" in subsystem Orphan regulatory proteins

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See I7F2E3 at UniProt or InterPro

Protein Sequence (313 amino acids)

>PGA1_262p01360 transcriptional regulator, LysR family (Phaeobacter inhibens DSM 17395)
MSRIATPNSRATMSRRHYDLPPLTTLAAFETAARHLSFKNAAQELSVTPGAVSHQIKALE
GELGVALFQRKHRGVELTREGQGLYESLATSFRQISRQLSKTRQMGEEDAVTVGSTTAVA
ALWLSPMIIQFWREYPDLNIHQITQDRPFHDTREFDFFIRYGRDRDAALAHTAIYRDQLV
PVARPDLAAGLDGASLQEIAQQRLIHLQSASQSWTTWADWFHELGHKGDIAAGTRVTSYS
VALQIARKGAGVALGWRRLIQPMLDSGKLAIVGCHSVPAPREFYLVGLPDDELSPNALKL
KQWILSQTRDTWL