Protein Info for PGA1_262p00850 in Phaeobacter inhibens DSM 17395

Annotation: putative sodium dependent symporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 485 transmembrane" amino acids 33 to 53 (21 residues), see Phobius details amino acids 58 to 76 (19 residues), see Phobius details amino acids 81 to 102 (22 residues), see Phobius details amino acids 107 to 124 (18 residues), see Phobius details amino acids 139 to 161 (23 residues), see Phobius details amino acids 166 to 185 (20 residues), see Phobius details amino acids 195 to 215 (21 residues), see Phobius details amino acids 238 to 261 (24 residues), see Phobius details amino acids 283 to 299 (17 residues), see Phobius details amino acids 305 to 323 (19 residues), see Phobius details amino acids 335 to 356 (22 residues), see Phobius details amino acids 362 to 379 (18 residues), see Phobius details amino acids 383 to 404 (22 residues), see Phobius details amino acids 421 to 444 (24 residues), see Phobius details amino acids 455 to 480 (26 residues), see Phobius details PF00939: Na_sulph_symp" amino acids 48 to 484 (437 residues), 85.7 bits, see alignment E=3.7e-28 PF03600: CitMHS" amino acids 71 to 426 (356 residues), 69.9 bits, see alignment E=2.2e-23

Best Hits

KEGG orthology group: None (inferred from 50% identity to mme:Marme_1249)

Predicted SEED Role

"Arsenic efflux pump protein" in subsystem Arsenic resistance

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See I7F2A5 at UniProt or InterPro

Protein Sequence (485 amino acids)

>PGA1_262p00850 putative sodium dependent symporter (Phaeobacter inhibens DSM 17395)
MTDQSNSAPPTSAHQLTGAGRSLSQMLRNKRSLWTVVLILTCAGLSAFATSIYLSPDLMG
VAALSVGAVGLWATGLVPEYWTALAFFLVAVIFSVAAPETIFSGFHSSTFWLLFSGLVLG
AAIKHTTLDKRAAGILALLPLRSYGGLLTGIVVFSVALAFVMPSSIGRIMILLPVISALA
ERVGFGAASNGRTGMLAVATFGTFAPAFTILPANAPNMILVGMSETIYGINISYFDYLLL
HFPVLGVVKSAVLVGLAMVMFPDRIPTHSIKAAPSAAPFSRQERILSLVLALCLLLWLTD
QIHMVSPAWVGMAAALICLLPGADLTRKGCINTDLSYGALLFVAGIMGLGAVISSAGLGE
AVVGAITGTVAFAVEWPVWNTSILIGLSTLVAMITNLPGVPAVMTPLAGELSDATGLPLE
TVLMTQVVAFSNVFLPFQAPPLIAAIQAGNLPAGAVIRLCLSLFLISLLLLAPLDLLWWH
LLGMF