Protein Info for PGA1_262p00730 in Phaeobacter inhibens DSM 17395

Annotation: putative signal transduction histidine kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 363 PF13581: HATPase_c_2" amino acids 18 to 108 (91 residues), 31.5 bits, see alignment E=3.3e-11 amino acids 251 to 336 (86 residues), 38.9 bits, see alignment E=1.7e-13 PF07536: HWE_HK" amino acids 162 to 216 (55 residues), 27.7 bits, see alignment 7.6e-10 PF07568: HisKA_2" amino acids 162 to 233 (72 residues), 54.2 bits, see alignment E=2.5e-18 PF02518: HATPase_c" amino acids 262 to 355 (94 residues), 36 bits, see alignment E=1.7e-12

Best Hits

Predicted SEED Role

"putative signal transduction histidine kinase with PAS/PAC domain"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See I7F4I4 at UniProt or InterPro

Protein Sequence (363 amino acids)

>PGA1_262p00730 putative signal transduction histidine kinase (Phaeobacter inhibens DSM 17395)
MAITKALQFGTFSQTRAVTALLEAARNAQQHASVGRVRLSLQEHGNKVAMRAIITDQGPG
IDGLDDILRGRRGGVAPGPGLGLGLRGLSRLSDHHTIRSGPEGTEIELLFLSPVKSAGMI
AAAQAATDAISKIRDADPVAELAEQNRMLLEALTERDLLMKEVHHRTGNNLALIGALIRM
SRRGAEAPETVSVLSDLEARVQSVIRVHEQLQRSARVDHLQALPFLQEVAANAEGAFNSE
ILKVSVSVRGDDIEIPSSMAIDLGLLTGELLTNAYKHAFVGREQGNILVELSEQDDALQL
VIADDGRGLAEGDARPERSGSLGWRMIRSMVGKYAGTTEVDGSNGMRVQFTLPFAREHTD
KSA