Protein Info for PGA1_262p00520 in Phaeobacter inhibens DSM 17395

Annotation: putative multi antimicrobial extrusion protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 444 transmembrane" amino acids 12 to 35 (24 residues), see Phobius details amino acids 53 to 75 (23 residues), see Phobius details amino acids 96 to 119 (24 residues), see Phobius details amino acids 135 to 156 (22 residues), see Phobius details amino acids 166 to 187 (22 residues), see Phobius details amino acids 196 to 218 (23 residues), see Phobius details amino acids 257 to 278 (22 residues), see Phobius details amino acids 285 to 302 (18 residues), see Phobius details amino acids 322 to 344 (23 residues), see Phobius details amino acids 359 to 379 (21 residues), see Phobius details amino acids 387 to 406 (20 residues), see Phobius details amino acids 411 to 434 (24 residues), see Phobius details TIGR00797: MATE efflux family protein" amino acids 21 to 412 (392 residues), 166.7 bits, see alignment E=3.9e-53 PF01554: MatE" amino acids 21 to 182 (162 residues), 78.1 bits, see alignment E=3.2e-26 amino acids 246 to 407 (162 residues), 83.2 bits, see alignment E=8.4e-28

Best Hits

Predicted SEED Role

"Multi antimicrobial extrusion protein (Na(+)/drug antiporter), MATE family of MDR efflux pumps" in subsystem Multidrug Resistance Efflux Pumps

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See I7E683 at UniProt or InterPro

Protein Sequence (444 amino acids)

>PGA1_262p00520 putative multi antimicrobial extrusion protein (Phaeobacter inhibens DSM 17395)
MAQKNLTQGAVWRALAAVSAPMSLGILGVLSVGLADAYFLGQLGEAPLAAVGFIYPVTTA
VTSLSIGLSAGANAAISQSLGRGDSAIETNRLSVHAIVLGTLVATLVALVFYLGAGALFS
VMGAKDDVLAEAQSYAPFWALSFPFLVGMALLNAVFRAHGDGATSAVIMMVAAALNIALD
PVLIYGLGPVPEMSTAGAALATALARVLTLIGAFGYALRTGVIRPPEVFTDGIGGSVREV
IRVGLPAAFSNAINPAGMAMVTAAAATLGDTVVAGLGAAQRVQSVALVPLLALSAGIGPV
VGQNWGADQQMRARLAVWQSWQFCIGYGLAMALVLTLFASDIAGLLTSDQGAAATTAQYL
RIVSWSFLGYGVLVTANAAMNARSKAVWSMGLSLMRIFAIYVPLAWLGVWIFGYAGILGA
AVIANLAAVPGAYFTGRRTGLVAR