Protein Info for HP15_355 in Marinobacter adhaerens HP15

Annotation: FeS cluster insertion

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 117 PF01521: Fe-S_biosyn" amino acids 12 to 112 (101 residues), 74.2 bits, see alignment E=4.9e-25 TIGR00049: iron-sulfur cluster assembly accessory protein" amino acids 14 to 116 (103 residues), 131.3 bits, see alignment E=7.2e-43

Best Hits

Swiss-Prot: 93% identical to ERPA_MARHV: Iron-sulfur cluster insertion protein ErpA (erpA) from Marinobacter hydrocarbonoclasticus (strain ATCC 700491 / DSM 11845 / VT8)

KEGG orthology group: None (inferred from 93% identity to maq:Maqu_0694)

Predicted SEED Role

"probable iron binding protein from the HesB_IscA_SufA family"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See E4PLW3 at UniProt or InterPro

Protein Sequence (117 amino acids)

>HP15_355 FeS cluster insertion (Marinobacter adhaerens HP15)
MSAVQQQIATPLFFSDSAVAKVRELIEEEENPELKLRVFVTGGGCSGFQYGFSFDESQDE
EDTVIERDGVSLLVDPMSYQYLVGATIDYQEGLQGSQFVVQNPNASSTCGCGSSFSI