Protein Info for HP15_3402 in Marinobacter adhaerens HP15

Annotation: undecaprenyl pyrophosphate phosphatase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 265 signal peptide" amino acids 1 to 25 (25 residues), see Phobius details transmembrane" amino acids 40 to 59 (20 residues), see Phobius details amino acids 80 to 104 (25 residues), see Phobius details amino acids 116 to 134 (19 residues), see Phobius details amino acids 149 to 165 (17 residues), see Phobius details amino acids 185 to 205 (21 residues), see Phobius details amino acids 216 to 238 (23 residues), see Phobius details amino acids 244 to 264 (21 residues), see Phobius details TIGR00753: undecaprenyl-diphosphatase UppP" amino acids 6 to 257 (252 residues), 241.5 bits, see alignment E=5.9e-76 PF02673: BacA" amino acids 6 to 258 (253 residues), 260.4 bits, see alignment E=1e-81

Best Hits

Swiss-Prot: 93% identical to UPPP_MARHV: Undecaprenyl-diphosphatase (uppP) from Marinobacter hydrocarbonoclasticus (strain ATCC 700491 / DSM 11845 / VT8)

KEGG orthology group: K06153, undecaprenyl-diphosphatase [EC: 3.6.1.27] (inferred from 93% identity to maq:Maqu_3641)

Predicted SEED Role

"Undecaprenyl-diphosphatase (EC 3.6.1.27)" (EC 3.6.1.27)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.6.1.27

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See E4PF95 at UniProt or InterPro

Protein Sequence (265 amino acids)

>HP15_3402 undecaprenyl pyrophosphate phosphatase (Marinobacter adhaerens HP15)
MDVFQALFLGLLQGLTEFLPISSSAHLILTPALFGWTDQGVGFDLSVHVGTLLAVVLYFR
RDVFGIARDGMISVSRRKIVGQGALAWYLVIGTIPAGLAGLALLDMIDNELRAVEVIFFT
TLFFGLLLGLADWLPKRQRTLDKLNWKDAVLVGIAQAMALVPGTSRSGVTITAGLFLGMT
RETASRFSFLLAIPIIVLASAVKLLEVATSDVIVDWSGFLIGGVTSFLMAITAIHFFLKW
LNKVGMWPYVIYRIVLAGVIYAVLM