Protein Info for HP15_3392 in Marinobacter adhaerens HP15

Annotation: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1199 TIGR02176: pyruvate:ferredoxin (flavodoxin) oxidoreductase" amino acids 5 to 1178 (1174 residues), 1656.7 bits, see alignment E=0 PF01855: POR_N" amino acids 17 to 247 (231 residues), 257 bits, see alignment E=1.4e-79 PF17147: PFOR_II" amino acids 269 to 351 (83 residues), 46.8 bits, see alignment 2.4e-15 PF01558: POR" amino acids 431 to 614 (184 residues), 100.4 bits, see alignment E=9.8e-32 PF10371: EKR" amino acids 631 to 683 (53 residues), 86.6 bits, see alignment (E = 5.7e-28) PF00037: Fer4" amino acids 688 to 710 (23 residues), 21.2 bits, see alignment (E = 1.4e-07) amino acids 745 to 763 (19 residues), 24.5 bits, see alignment (E = 1.4e-08) PF13237: Fer4_10" amino acids 690 to 762 (73 residues), 25.1 bits, see alignment 1.1e-08 PF13183: Fer4_8" amino acids 691 to 764 (74 residues), 28.8 bits, see alignment 1.1e-09 PF13484: Fer4_16" amino acids 694 to 763 (70 residues), 31.6 bits, see alignment 1.8e-10 PF12838: Fer4_7" amino acids 694 to 763 (70 residues), 39.8 bits, see alignment 3.8e-13 PF13187: Fer4_9" amino acids 694 to 764 (71 residues), 28.5 bits, see alignment 9.4e-10 PF02775: TPP_enzyme_C" amino acids 968 to 1079 (112 residues), 42.1 bits, see alignment E=6e-14

Best Hits

Predicted SEED Role

"Pyruvate-flavodoxin oxidoreductase (EC 1.2.7.-)" in subsystem Methionine Degradation or Pyruvate:ferredoxin oxidoreductase (EC 1.2.7.-)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.2.7.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See E4PRQ9 at UniProt or InterPro

Protein Sequence (1199 amino acids)

>HP15_3392 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein (Marinobacter adhaerens HP15)
MAMEFHTLDGNEAVSSVAYRLSETIAIYPITPASVMGEHADDWAALGKPNLWGQVPSVVE
MQSEAGAAGAMHGALQAGSLVTTFTASQGLLLMLPNLYKIAGELSPFCMHIAARSIATHA
LSIFCDHSDVMSARGTGFALLASGSVQEAQDLAAIGHAVTLESRVPVMHFFDGFRTSHEI
SKIAALSNEDLQALVSHEGVEAHRSRRMTPDRPVVRGTSQNPDAFFQAREAINPFYEAFP
EKLAAVMDRFAGITGRQYRLFDYVGHPEADRVVILMGSGAECAHETVEWLLEQGEKVGVL
KVRLFRPFATARFLDALPDTVEHLAVLDRTKEPGAQGEPLLLEVSGALMEAYSRGDRKVL
PRVIGGRYGLSSREFTPAMVCAIFDELKAEAPKTRFTVGVRDDVSHLSLEVDSELDIESP
KTRRALFFGLGADGTVSSNKASIKILGEGTELFAQGHFVYDSKKSGATTVSHLRFGPLPI
RSSYQINRAQFVAIHAPQFLERFDVLEHAAEGATVLLNVPWSKDEIWDRLSVEVQRVLVE
RKARLFVIDAAEVAEKAGLERRINTVMQVCFFALADILPREEAIAHIKESIRKTWGRRGP
EVVRRNVEAVDSALDDLHEVPVPHKVTATRTRPPRVPENAPDFVQKVTRLLLEGQGDKLP
VSAFPPDGTWPTGTSQYEKRTIALEIPIWESDLCVQCNFCAMICPHTAITSKVFEPESVK
GAPEAFEVVPETQTSELEGLDYRIQVAPDDCTGCGLCVEVCPAKDRTQPKRKAINMQPIE
AYREVEAENLAFFRQLPDVPRDRIPRDFKSLPLLIPLFEYSGACSGCGETPYIRLLTQLV
GDRLLIANATGCSSIYGGNLPTTPYTVNADGRGPTWNNSLFEDAAELGLGMRLGLDKLVG
RARQLLEGFREELPDGLYPELTSACTTVDESAMAARRTAIEQLRNWLADKQTPEARELDS
LADELCPKSVWVVGGDGWAYDIGYGGLDHALASGQNVKLLVLDTEVYSNTGGQQSKATPM
GAIAKFAAAGKATRKKDLGLLAMSYGHVYVAQIAMQSHSNHTTKALQEAESFDGPALIIA
HSPCIAHGYDLVHSPAQQKRAVDSWAWPLYRFDPRRIHEGLPPLQLDSLRQKVTMKAYMQ
EEARFRMLELRDPQRYEQLVAAASEAATEQRELYKQLAGIHFEPHETSDADNEKGERHD