Protein Info for Psest_3498 in Pseudomonas stutzeri RCH2

Annotation: haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED/haloacid dehalogenase superfamily, subfamily IA, variant 1 with third motif having Dx(3-4)D or Dx(3-4)E

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 TIGR01509: HAD hydrolase, family IA, variant 3" amino acids 8 to 170 (163 residues), 35 bits, see alignment E=1.5e-12 TIGR01549: HAD hydrolase, family IA, variant 1" amino acids 10 to 164 (155 residues), 37.5 bits, see alignment E=3.1e-13 PF00702: Hydrolase" amino acids 10 to 164 (155 residues), 78.1 bits, see alignment E=2.4e-25 PF13419: HAD_2" amino acids 38 to 169 (132 residues), 62.7 bits, see alignment E=1e-20 PF13242: Hydrolase_like" amino acids 127 to 171 (45 residues), 35.1 bits, see alignment 2e-12

Best Hits

KEGG orthology group: None (inferred from 92% identity to psa:PST_0885)

Predicted SEED Role

"Hydrolase in polyol utilization gene cluster, haloacid dehalogenase-like family" in subsystem Mannitol Utilization or Ribitol, Xylitol, Arabitol, Mannitol and Sorbitol utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0GQD7 at UniProt or InterPro

Protein Sequence (200 amino acids)

>Psest_3498 haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED/haloacid dehalogenase superfamily, subfamily IA, variant 1 with third motif having Dx(3-4)D or Dx(3-4)E (Pseudomonas stutzeri RCH2)
MRIAEVRHWVFDMDGTLTIAVHDFAAIRRALEIPEEDDILHHLAALPAEEAAAKHAWLLE
HERELAYAARPAEGARELLHTLRERGCRLGVLTRNAHELAKVTLDAVGMGDCFLPEDILG
RDEAPPKPHPGGLLHLAQRWGVAPAAMLMVGDYRFDLECARAAGARGVLVNVPHNEWPEL
TDLYARDCRVLHGLLSSGEA