Protein Info for HP15_3365 in Marinobacter adhaerens HP15

Annotation: D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 805 PF09364: XFP_N" amino acids 62 to 302 (241 residues), 51.8 bits, see alignment E=5.7e-18 PF03894: XFP" amino acids 433 to 602 (170 residues), 148.3 bits, see alignment E=2e-47

Best Hits

KEGG orthology group: None (inferred from 81% identity to maq:Maqu_3607)

Predicted SEED Role

"Xylulose-5-phosphate phosphoketolase (EC 4.1.2.9) @ Fructose-6-phosphate phosphoketolase (EC 4.1.2.22)" (EC 4.1.2.22, EC 4.1.2.9)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 4.1.2.22 or 4.1.2.9

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See E4PRN2 at UniProt or InterPro

Protein Sequence (805 amino acids)

>HP15_3365 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase (Marinobacter adhaerens HP15)
MPFPIQTAAVNHAASDCPDFRRWCDGYGVIQHSEATQHQVSLLAEHLVAAGHQPDAATVY
RKLADLDRLTSAGLWLVVHMTYARRVDVSGQPLAPQDFKTNPEGHTGGALNMVPAYAGYL
ALNNLTGRTRSWLMGQGHCVAAVDALNVLTGNLHPEQAERYRGPDGLSTLVSDFYSYRQK
PDGTMAAPLGSHVNPHTAGGILEGGYLGFAELQYAHMPLPGESLVAFLSDGAAEEQRGSD
WIPRWWRAEDCGAVMPVMIANGRRIEQRTELGTREGLERFEAHLEHRGFVPFRFDGRDPA
AFVCALYEMEQALATNGEAALRGESGYPVRVPYGIAETTKGYGFYGASSNAAHNLPLPGN
PRMDARARELFNEHAARLWVAPDQLQNAITHLNQHTGQSRPLERDHALATRNPPDPIIPR
LPACRECTSPMKAVDDFFRALVAQNPDLRARVGNPDELASNRLGGVLDDLKHRVNDPEND
QESVHGKIITALNEESVVSACLANKAGLNLVASYEAFCVKMLGAIRQELIFARHQKEIGR
PARWLGLPVIATSHTWENGKNEQSHQDTTFCESMLAEMNDVSRVVFPADYNSTLATLPSV
FRERGTISCMVIPKRERPCVFDTREAELLARHGALVVDEDTSSGEPLLLIANGAYQLSES
IRACERLRETGTPFRLVYIQEPGRFRQPRDTMEAQVCLSEFERERLFPHRIRRRVALTHM
RPEVFRGHLHPLFPEPSQARVLGYINRGGTLNEAGMLFANGCSWGHALAACASVMDKPPG
EWLSSAELAAVEGRGDPAVITRGLP