Protein Info for HP15_3327 in Marinobacter adhaerens HP15

Annotation: GTP-binding protein EngB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 215 TIGR03598: ribosome biogenesis GTP-binding protein YsxC" amino acids 15 to 200 (186 residues), 235.7 bits, see alignment E=1.6e-74 PF01926: MMR_HSR1" amino acids 34 to 153 (120 residues), 68.9 bits, see alignment E=2.1e-23

Best Hits

Swiss-Prot: 61% identical to ENGB_ALCBS: Probable GTP-binding protein EngB (engB) from Alcanivorax borkumensis (strain ATCC 700651 / DSM 11573 / NCIMB 13689 / SK2)

KEGG orthology group: K03978, GTP-binding protein (inferred from 94% identity to maq:Maqu_3570)

Predicted SEED Role

"GTP-binding protein EngB" in subsystem Universal GTPases

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See E4PRJ4 at UniProt or InterPro

Protein Sequence (215 amino acids)

>HP15_3327 GTP-binding protein EngB (Marinobacter adhaerens HP15)
MDPDLTQKSLSFNSARFLISASRLDECPPDFGAEVAFAGRSNAGKSSALNAITANGKLAR
TSKTPGRTRLINFFSLNRENCRMVDLPGYGYAKVSRDMKDDWQKHLGHYLNDRRCLRGLV
LVMDIRHPLTDFDQMMVEWCEHNNLPLMILATKADKLKYGQAKTAMLGIAKNLKSYSCVE
HLIMFSATSKRGVDECREALIEWLEGDAGEAETTA