Protein Info for HP15_3280 in Marinobacter adhaerens HP15

Annotation: survival protein surA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 446 signal peptide" amino acids 1 to 27 (27 residues), see Phobius details PF13624: SurA_N_3" amino acids 12 to 147 (136 residues), 48.7 bits, see alignment E=2.3e-16 PF13623: SurA_N_2" amino acids 31 to 113 (83 residues), 36.4 bits, see alignment E=1.4e-12 PF09312: SurA_N" amino acids 31 to 148 (118 residues), 140 bits, see alignment E=1.3e-44 PF13616: Rotamase_3" amino acids 171 to 280 (110 residues), 52.1 bits, see alignment E=2.9e-17 amino acids 284 to 388 (105 residues), 102.8 bits, see alignment E=5.2e-33 PF00639: Rotamase" amino acids 185 to 278 (94 residues), 58.4 bits, see alignment E=3.5e-19 amino acids 295 to 386 (92 residues), 88.7 bits, see alignment E=1.3e-28 PF13145: Rotamase_2" amino acids 295 to 391 (97 residues), 28.2 bits, see alignment E=8.7e-10

Best Hits

Swiss-Prot: 48% identical to SURA_HAHCH: Chaperone SurA (surA) from Hahella chejuensis (strain KCTC 2396)

KEGG orthology group: K03771, peptidyl-prolyl cis-trans isomerase SurA [EC: 5.2.1.8] (inferred from 76% identity to maq:Maqu_3509)

Predicted SEED Role

"Survival protein SurA precursor (Peptidyl-prolyl cis-trans isomerase SurA) (EC 5.2.1.8)" in subsystem Peptidyl-prolyl cis-trans isomerase (EC 5.2.1.8)

Isozymes

Compare fitness of predicted isozymes for: 5.2.1.8

Use Curated BLAST to search for 5.2.1.8

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See E4PQY7 at UniProt or InterPro

Protein Sequence (446 amino acids)

>HP15_3280 survival protein surA (Marinobacter adhaerens HP15)
MKATLRHGVQALLVLLAVLAPLSVQAERKLLDQVVAIVDEDVILQTELEARINTITSRLG
AQGTALPPRQVLEERVLDQLITESIQMQMADRAGMRISDNELNETMANIAERNGMSLPQF
ENQLEAEGVTYNQAREQIRKEMLTSRVQQRQVGNRVRVTDREVENYLESLEARGGNNAQY
RLAYIFVSVDDPSDEAEVDAAREKAERLRSEIANGRDFREVAVAESDASNALEGGDMGWR
AEGQLPSLVAPVVPELPVGEPSDVLENNSGFHLVMVMDKRGGEQQQMIQQHRVRHILVRP
SEATTDSQAETVIRDLYQQLQNGASFSALAREYSDDPVSGSDGGNLGWVSPGQMVPAFEQ
AMLDADIGELRGPFRSQFGWHILQVQERRQKDISGDVRDAEARQAIYRRKFETELQNWLQ
EIRDEAFVEFKGEYAKDEPAEEEPVS