Protein Info for PGA1_c03420 in Phaeobacter inhibens DSM 17395

Annotation: putative C-5 sterol desaturase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 309 transmembrane" amino acids 12 to 31 (20 residues), see Phobius details amino acids 43 to 70 (28 residues), see Phobius details amino acids 80 to 99 (20 residues), see Phobius details amino acids 147 to 170 (24 residues), see Phobius details PF04116: FA_hydroxylase" amino acids 87 to 221 (135 residues), 103 bits, see alignment E=8.8e-34

Best Hits

KEGG orthology group: None (inferred from 81% identity to sil:SPO0328)

Predicted SEED Role

"Mll1065 protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See I7DLQ1 at UniProt or InterPro

Protein Sequence (309 amino acids)

>PGA1_c03420 putative C-5 sterol desaturase (Phaeobacter inhibens DSM 17395)
MPDTISYPDVTQWAVPFFIAAILAEFLWIAIKRRGGRYETRDAVTSLVMGAGSVASGIAL
GFIAWAFFMLLWQITPLDLGTSLWVIALCFVLDDLRYYWVHRFGHRVRWVWASHVNHHSS
QHYNLTTALRQTWTGTFTFMMVVRAPLVLLGFHPAMVLFVGGINLVYQFWIHTEAIGRMP
RWFEAVMNTPSHHRAHHGRNPRYLDCNYAGVFIVWDKIFGTFVPEQDHDRPDYGLVHNIG
TFNPLRVAFHEWVSIFKDMTQPGLTPRQRLLYAVAPPGYSHDGSRDSSETIRAKHLQRHP
EDIGSAGFD