Protein Info for HP15_328 in Marinobacter adhaerens HP15

Annotation: two component, sigma54 specific, transcriptional regulator, Fis family

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 467 PF00072: Response_reg" amino acids 4 to 110 (107 residues), 85.3 bits, see alignment E=1e-27 PF00158: Sigma54_activat" amino acids 143 to 308 (166 residues), 241.3 bits, see alignment E=1.3e-75 PF14532: Sigma54_activ_2" amino acids 143 to 313 (171 residues), 69 bits, see alignment E=1.6e-22 PF07728: AAA_5" amino acids 166 to 285 (120 residues), 25.4 bits, see alignment E=3.9e-09 PF25601: AAA_lid_14" amino acids 314 to 385 (72 residues), 81.9 bits, see alignment E=7.5e-27

Best Hits

KEGG orthology group: None (inferred from 87% identity to maq:Maqu_0670)

Predicted SEED Role

"Two-component sensor CbrB: intrcellular carbon:nitrogen balance"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See E4PL50 at UniProt or InterPro

Protein Sequence (467 amino acids)

>HP15_328 two component, sigma54 specific, transcriptional regulator, Fis family (Marinobacter adhaerens HP15)
MPRILIVEDEDIIRSAVRKLLLHAGYEVADAASVEEAEQNHEPDQFDLIISDLRLPGAAG
TELINRAPNTPVLIMTSYASLRSAVDSMKMGAVEYIAKPFDHDEMLAAVENILARKPAGR
NSGDDSAPALETPESSDPANIMFGQCEPMQRVFTLIRKVAPTETTVLIQGESGTGKELAA
RALHLLSPRAAKPLISVNCAAIPESLIESELFGHEKGAFTGAVSARTGLIEAADGGSLFL
DEIGELPAEAQARLLRVLQESEIRKVGSTQSRTVNVRMIAATHRNLKAMTRTGEFREDLY
YRLNVMQIRIPPLRERQSDILGLARRFLKRQGERMGKPDLNLSPEAMRALERHRWPGNVR
ELENAIERATILCDGDVITPSLLDLDSEGSDEYIPETLVDGNNEQTHTREVDASNDLSLE
DYFQHFVLENQDRMSETELAQKLGISRKSLWERRQRLGIPRKKSSGN