Protein Info for PGA1_c03330 in Phaeobacter inhibens DSM 17395

Annotation: tetratricopeptide repeat-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 582 signal peptide" amino acids 1 to 33 (33 residues), see Phobius details PF13432: TPR_16" amino acids 143 to 198 (56 residues), 17.1 bits, see alignment 5e-06 amino acids 294 to 335 (42 residues), 16.5 bits, see alignment 7.7e-06 amino acids 342 to 399 (58 residues), 31.1 bits, see alignment 2.1e-10 amino acids 412 to 443 (32 residues), 16 bits, see alignment (E = 1.1e-05) amino acids 459 to 509 (51 residues), 24.6 bits, see alignment 2.2e-08 PF13174: TPR_6" amino acids 304 to 335 (32 residues), 16.3 bits, see alignment (E = 9.9e-06) amino acids 339 to 369 (31 residues), 13.8 bits, see alignment (E = 6.5e-05) PF13181: TPR_8" amino acids 373 to 400 (28 residues), 13 bits, see alignment (E = 8.3e-05) amino acids 412 to 441 (30 residues), 13.7 bits, see alignment (E = 4.7e-05) PF13424: TPR_12" amino acids 374 to 440 (67 residues), 31.2 bits, see alignment E=1.6e-10 PF07719: TPR_2" amino acids 410 to 441 (32 residues), 27.4 bits, see alignment (E = 2e-09) PF13374: TPR_10" amino acids 483 to 507 (25 residues), 15.9 bits, see alignment (E = 8.4e-06)

Best Hits

KEGG orthology group: None (inferred from 68% identity to sit:TM1040_3744)

Predicted SEED Role

"FIG140336: TPR domain protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See I7DLP2 at UniProt or InterPro

Protein Sequence (582 amino acids)

>PGA1_c03330 tetratricopeptide repeat-containing protein (Phaeobacter inhibens DSM 17395)
MPVRFFRSLTCAAALAATTTLPMLLQADAAHADGLAGAYLAARAATLDSDFQASADYYNR
ALVRDPQNPLLMEHVVFARLALGDIKGAAPVAERLSEMGARSQVANIVMTASLVMAEDYP
AIIERVTSQPDGQYEINALVDGLLLGWAHLGAGSVSDALAQFDQLGEKEGLSLFARYHRA
LALASVGDYEGAEALFAADEGQLTNTSRRAVIARLEILSQLGRNDKALEVLSEAFSGQLD
PGLAALSERLQNDETLPYALAATPQQGIAEVFFTMGAALNGEMADDYVLMYARVAAALRE
DHVDALLLAAELFDQLGRYTLSIDLYKQVPRDHPDYHAAELGRAEALRRAAKPDAAAEVL
QQLARDFPKEVPVHTNLGDLLRQQEDYGGAVAAYDTALDLMDESVEGRWFLLYARGICHE
RLKNWEQAEADFRAALEIRPDQPQVLNYLGYSLVEKQIKLDEALSMIERAVAARPDAGYI
VDSLGWVLYRLGRYEEAVGHMETAVELMPVDPVVNDHLGDVYWAVGRAREAEFQWKRALS
FIDPEDTDSEADPDRIRRKLETGLDAVLAEEGAAPLKVAHDG