Protein Info for Psest_3260 in Pseudomonas stutzeri RCH2

Annotation: cell division protein FtsW

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 407 transmembrane" amino acids 20 to 42 (23 residues), see Phobius details amino acids 61 to 82 (22 residues), see Phobius details amino acids 88 to 107 (20 residues), see Phobius details amino acids 120 to 142 (23 residues), see Phobius details amino acids 153 to 171 (19 residues), see Phobius details amino acids 176 to 195 (20 residues), see Phobius details amino acids 200 to 217 (18 residues), see Phobius details amino acids 286 to 306 (21 residues), see Phobius details amino acids 318 to 340 (23 residues), see Phobius details amino acids 354 to 373 (20 residues), see Phobius details signal peptide" amino acids 43 to 43 (1 residues), see Phobius details TIGR02614: cell division protein FtsW" amino acids 23 to 378 (356 residues), 417.7 bits, see alignment E=1.9e-129 PF01098: FTSW_RODA_SPOVE" amino acids 26 to 380 (355 residues), 338.7 bits, see alignment E=2e-105

Best Hits

Swiss-Prot: 79% identical to FTSW_PSEFS: Probable peptidoglycan glycosyltransferase FtsW (ftsW) from Pseudomonas fluorescens (strain SBW25)

KEGG orthology group: K03588, cell division protein FtsW (inferred from 97% identity to psa:PST_1081)

MetaCyc: 44% identical to peptidoglycan glycosyltransferase FtsW (Escherichia coli K-12 substr. MG1655)
Peptidoglycan glycosyltransferase. [EC: 2.4.1.129]

Predicted SEED Role

"Cell division protein FtsW" in subsystem Bacterial Cell Division or Bacterial Cytoskeleton

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.4.1.129

Use Curated BLAST to search for 2.4.1.129

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0GPN4 at UniProt or InterPro

Protein Sequence (407 amino acids)

>Psest_3260 cell division protein FtsW (Pseudomonas stutzeri RCH2)
MLAFLRNAPSPLFGRRGVDLDFPMLAGCLALLGLGLVMITSASSEVAAVNSGSPLYHMIR
HLIYVLLGLGAAAAMLLVPLSVWQRLDWMLLLAAFGLLILVLLPGIGREVNGSMRWIGFG
AFNVQPSELAKVFVVIYLAGYLVRRQEEVRESLWGFAKPFLVLLPMAFLLLMEPDFGATV
VMMGAAVAMLFLGGVGMIRFSLLVIAAVGAVVVLVQTQEYRLQRLITFTDPWADQYGAGY
QLTQALIAFGRGEWFGVGLGNSVQKQFYLPEAHTDFVFSVLAEELGMVGALATIALFAFV
GVRALYIGLWAEKARQFFAAYVAWGLAFLWLGQFLINVGVNVGLLPTKGLTLPFLSYGGS
SLVVTCASMALLLRIEWESRTVLGSEDTEFDEADFAEPPSKEVAHGR