Protein Info for PGA1_c32060 in Phaeobacter inhibens DSM 17395
Annotation: glutathione-binding protein GsiB
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
KEGG orthology group: K02035, peptide/nickel transport system substrate-binding protein (inferred from 80% identity to sil:SPO0101)Predicted SEED Role
"Peptide/opine/nickel uptake family ABC transporter, periplasmic substrate-binding protein"
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See I7ERB3 at UniProt or InterPro
Protein Sequence (492 amino acids)
>PGA1_c32060 glutathione-binding protein GsiB (Phaeobacter inhibens DSM 17395) MTRLPFLFAASSALAILAGAAAARDTVTVALQLEPPHLDPTSAAAGAIDQVLYSNVFEGL TRFMGDGSVVPGLAQSWGISEDGLSYTFTLQDGVTFHDGTTMDAEDVKFSLDRARAEDST NAQKALFADIASVDVVDPLTVKLTLSQPNGNLLFNLAWGDAVIVAPETIDTIKTAPVGTG AFTFTNWVQGDRIDLARNPDYWGEAPALSAATFKFISDPTAAFAAMMAEDIDAFSAFPAP ENLPQFEADPRFQVLIGSTEGETILSINNKQAPFDNPKVRAAVAHAIDRQAIIDGAMFGY GTPIGSHFAPHNPAYIDLTGTSAHDPEKARALLAEAGLADGFTTTLHLPPPSYARRGGEI IAAQLAEVGITAEIINVEWAQWLETVFRGKNFGLSIVSHTEPMDIGIYARPDYYFQYDNA AFQDLMAELTGTTDPDARTKMLQQAQEIIANDYVNGYLFQLAALSVAKADLQGLWANAPT QATDLTVVSWAK