Protein Info for PGA1_c31840 in Phaeobacter inhibens DSM 17395

Annotation: N-terminal double-transmembrane domain

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 900 972 transmembrane" amino acids 6 to 28 (23 residues), see Phobius details amino acids 61 to 83 (23 residues), see Phobius details amino acids 640 to 664 (25 residues), see Phobius details amino acids 675 to 693 (19 residues), see Phobius details PF07584: BatA" amino acids 7 to 81 (75 residues), 68.4 bits, see alignment 6.1e-23 TIGR02226: N-terminal double-transmembrane domain" amino acids 9 to 86 (78 residues), 49.2 bits, see alignment E=2.5e-17 PF13709: DUF4159" amino acids 733 to 952 (220 residues), 186.6 bits, see alignment E=3.9e-59

Best Hits

Predicted SEED Role

"FIG003603: membrane protein, putative"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See I7DUU3 at UniProt or InterPro

Protein Sequence (972 amino acids)

>PGA1_c31840 N-terminal double-transmembrane domain (Phaeobacter inhibens DSM 17395)
MTTIAGIGFTAPWLLLALLALPLLWLLLRAVPPAPRTRLFPAVTLLLGLRDDDSLSDRTP
WWLLLLRLMAVAAAIVGLAGPVLNPTATPTGRGPLLVVLDGSWAGAPDWDRTREEIDHLL
AEAGRADRPVAVLRLTAPQPPEFQSAASWRRQIIGEAPQAWQPTPEQLARARTQIDTLEG
GFDSLWFSDGLTYAGRDDLLATLRQRGRLTVYEHATPRLALRPVVYVDGAMEITVVRSSP
QAASGDGRGATGPGAGEDQTVTVLAKGPDPGGTMRTLGSVTVDFADPDSTSADGSEATAR
LSLPAELRARIRLFELQGQTSAGAVSLADDGLRRREVALISAQSGNEGLALLSPLHYLRK
ALAPTADLLEGGLSDLLPANPDVIVLADTARLPPDQEAAVVDWASDGGLLLRFAGPRLAA
SDTARTDEEPLLPVRLRIGGRSIGGAMSWGEPKTLAPFAEDSPFFGLNIPPDVTVSSQVV
AQPDPSLAERVIAELSDGTPLVTRKPLGNGQIVLFHVTANAEWSSLPLSGLFVQMMERLA
ISSGSKPAEAVDLEGTTWAPLQVLDGFGDLFDADALPGVAGPDLIAATAGPELQPGLYQN
GDRRIARNVMRTEDQLTPAQWPLGVPVNGYGATPERPLGGLLISLALLLLALDVIAALLL
SGLLPRQPQTSANKMRNMISLLLLATSVWVISPGHNTRSHAQGNAIAIEEVTPSPPSDPA
ADALAAERAAELTLAHVLTGDPQVDQLARDGLQGLSNTLRFRTSVEPAPPAAVDLERDEL
AFYPLLYWPVTANQAMPSGAAYDRLNTYLRTGGMILFDTRDADLTRAGASSPAGRRLQQL
ALRLDVPPLEPLPADHVLTRAFYLLQDFPGRHNRGAVWVEAAPADAQQVEGIPFRNLNDG
VTPVVIGGNDWAAAWAVDDNGRPLLPVGRGYAGERQRELAYRFGVNLVMHVLTGNYKSDQ
VHVPALLDRLGQ