Protein Info for HP15_3051 in Marinobacter adhaerens HP15

Annotation: thioredoxin domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 287 PF00085: Thioredoxin" amino acids 10 to 109 (100 residues), 95.5 bits, see alignment E=6e-31 TIGR01068: thioredoxin" amino acids 12 to 111 (100 residues), 99.1 bits, see alignment E=6.8e-33 PF13098: Thioredoxin_2" amino acids 25 to 108 (84 residues), 31.8 bits, see alignment E=5.4e-11 PF13905: Thioredoxin_8" amino acids 27 to 70 (44 residues), 27.5 bits, see alignment 1.2e-09 PF14559: TPR_19" amino acids 128 to 193 (66 residues), 51.9 bits, see alignment E=2.7e-17 PF14561: TPR_20" amino acids 198 to 287 (90 residues), 86.8 bits, see alignment E=3.6e-28

Best Hits

KEGG orthology group: K05838, putative thioredoxin (inferred from 82% identity to maq:Maqu_3331)

Predicted SEED Role

"FIG000875: Thioredoxin domain-containing protein EC-YbbN"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See E4PNY4 at UniProt or InterPro

Protein Sequence (287 amino acids)

>HP15_3051 thioredoxin domain-containing protein (Marinobacter adhaerens HP15)
MSNSPYIFDATMENFQQKVMEASASTPVLVDVWAEWCAPCKQLMPLLEKLAEDYQGAFML
AKVNADEQEQLTSSLGVRSLPTVILVKNGQAVDGFNGALPENEIRKVLDKHVEAPKEDPY
DKAHRIWEEGDVEGALAILSQMNQEDPENLKVLIDLAQLKAEMGDLETAEQVLESLPPEE
KMQHQAKQLAARLKFLRQSAELPPIKDLEMALEQDPKDPNALHQLALHHVLQENNAEAMD
LLIRLMQVDSKYKDEVAKTTLIELFDKLGNNNPDVRTYRRKLYTLMH