Protein Info for HP15_3038 in Marinobacter adhaerens HP15

Annotation: N-succinylarginine dihydrolase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 446 PF04996: AstB" amino acids 5 to 445 (441 residues), 713.4 bits, see alignment E=5e-219 TIGR03241: succinylarginine dihydrolase" amino acids 5 to 445 (441 residues), 736 bits, see alignment E=8.6e-226

Best Hits

Swiss-Prot: 88% identical to ASTB_MARHV: N-succinylarginine dihydrolase (astB) from Marinobacter hydrocarbonoclasticus (strain ATCC 700491 / DSM 11845 / VT8)

KEGG orthology group: K01484, succinylarginine dihydrolase [EC: 3.5.3.23] (inferred from 88% identity to maq:Maqu_3315)

MetaCyc: 56% identical to N-succinylarginine dihydrolase (Escherichia coli K-12 substr. MG1655)
N-succinylarginine dihydrolase. [EC: 3.5.3.23]

Predicted SEED Role

"Succinylarginine dihydrolase (EC 3.5.3.23)" in subsystem Arginine and Ornithine Degradation (EC 3.5.3.23)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.5.3.23

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See E4PNX2 at UniProt or InterPro

Protein Sequence (446 amino acids)

>HP15_3038 N-succinylarginine dihydrolase (Marinobacter adhaerens HP15)
MVKHAVEANFDGLVGPTHNYAGLSWGNVASKSNVSSVSNPKEAALQGLAKMKRLADRGYV
QGVLPPHERPHIPTLRALGFEGPDARVLEQAAKSSPSILAAVSSASPMWTANAATVSPSA
DTSDHRVHFTPANLSAKFHRSIEHAVTGRALKSIFADESYFAHHPALPSVSHFGDEGAAN
HTRLCAGYGEPGVELFVYGQMAFNEQAPAPKKYPARQTLEASQAVARLHGLRDQNAVFAQ
QNPDAIDGGVFHNDVIAVGNGNTLFYHEMAFLNEAQVLADIRERLTGAELEAVRVSSADV
PLEDAVASYLFNSQLLNTPDGMLLAVPGECREVASVSRYLDGLVKSGGPITAVEVFDVKQ
SMRNGGGPACLRLRVVLNDDELKAINRGVLLTDELYERLTTWVEAHYRDELSQNELGDPM
LLEEVRKALDELTGIMGLGSIYDFQL