Protein Info for HP15_3034 in Marinobacter adhaerens HP15

Annotation: succinylglutamate desuccinylase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR03242: succinylglutamate desuccinylase
  • amino acids 34 to 340 (307 residues), 313.7 bits, E=7.7e-98
• PF04952: AstE_AspA
  • amino acids 62 to 340 (279 residues), 188.4 bits, E=8.9e-60

Best Hits

Swiss-Prot: 39% identical to ASTE_SHEPW: Succinylglutamate desuccinylase (astE) from Shewanella piezotolerans (strain WP3 / JCM 13877)

KEGG orthology group: K05526, succinylglutamate desuccinylase [EC: 3.5.1.96] (inferred from 75% identity to maq:Maqu_3311)

Predicted SEED Role

"Succinylglutamate desuccinylase (EC 3.5.1.96)" in subsystem Arginine and Ornithine Degradation (EC 3.5.1.96)

MetaCyc Pathways

• L-arginine degradation II (AST pathway) (5/5 steps found)

KEGG Metabolic Maps

• Arginine and proline metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.5.1.96

Sequence Analysis Tools

See E4PNW8 at UniProt or InterPro

Protein Sequence (351 amino acids)

>HP15_3034 succinylglutamate desuccinylase (Marinobacter adhaerens HP15)
MTVSSDLFGSSHDWLSHTLDNADASLPETKAFLPDGTRISRKAVGVLDIVPPAARSNPNA
EAIIVSAGVHGNETAPIEVLNRLVSELIEGEWELACPVLLIMGNPPAMVAGKRFLEVNLN
RLFDGAHSRNEYEGLAEAARAQELEEACRQFAMANPQALYHYDLHTAIRPSHRERFALYP
FVEGRTVPVDQCDFLLEAEVETLLLQHKAGTTFSSFSSSLLKAESFTVELGKVRPFGQND
LGRFSGIRDALRRRFKGQPSPAPQPPFDHLTVFEVVHEILNTGKNFRFHIPDDVANFTEY
QPGTVIWEDDETSYRVGHSPEAIVFPNPEVPVGHRVGLMIRPETGSDESFI