Protein Info for PGA1_c30850 in Phaeobacter inhibens DSM 17395

Annotation: phosphoesterase-like protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF00149: Metallophos
  • amino acids 1 to 194 (194 residues), 62.8 bits, E=3.1e-21

Best Hits

Swiss-Prot: 47% identical to CPDA_RHOPA: 3',5'-cyclic adenosine monophosphate phosphodiesterase CpdA (cpdA) from Rhodopseudomonas palustris (strain ATCC BAA-98 / CGA009)

KEGG orthology group: None (inferred from 49% identity to bja:bll4141)

MetaCyc: 50% identical to phosphodiesterase subunit (Delftia acidovorans)
3.1.3.-

Predicted SEED Role

"3',5'-cyclic-nucleotide phosphodiesterase (EC 3.1.4.17)" in subsystem cAMP signaling in bacteria (EC 3.1.4.17)

MetaCyc Pathways

• diethylphosphate degradation (2/2 steps found)

KEGG Metabolic Maps

• Purine metabolism

Isozymes

Compare fitness of predicted isozymes for: 3.1.4.17

Use Curated BLAST to search for 3.1.4.17

Sequence Analysis Tools

See I7DUH3 at UniProt or InterPro

Protein Sequence (284 amino acids)

>PGA1_c30850 phosphoesterase-like protein (Phaeobacter inhibens DSM 17395)
MKFIHLTDTHVTGGDRLLYGANPARRLAQAVDSINAEHGDAAFVIVTGDMTHWGDAGAYA
AFRDKISRLDMPVHLMVGNHDDTAAFTEYFPNAPRDNNGFVQFTLDTPHGRAICLDTKSP
GTHAGSYCQARLDWLSARLQETNDPVLLFMHHPPFKVGIYAMDAIMMQDADAFHEVIAPH
KARIRHLFFGHVHRAIFGNWRGICFSCMRGLNHQVALDLTAGQSEIPGNLEPQAYGVVLV
DEAAVIVHMHDFMDSSPAFSLHAPESVDPVRYQLDMVHAGFKDL