Protein Info for PGA1_c30600 in Phaeobacter inhibens DSM 17395

Annotation: RTX toxins and related Ca2+-binding proteins

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 900 959 PF00353: HemolysinCabind" amino acids 13 to 41 (29 residues), 21.7 bits, see alignment (E = 1.6e-08) amino acids 34 to 66 (33 residues), 25.1 bits, see alignment (E = 1.4e-09) amino acids 272 to 304 (33 residues), 34.4 bits, see alignment (E = 1.8e-12) amino acids 287 to 322 (36 residues), 32.2 bits, see alignment (E = 8.4e-12) amino acids 297 to 331 (35 residues), 30.2 bits, see alignment (E = 3.4e-11) amino acids 324 to 358 (35 residues), 33.5 bits, see alignment (E = 3.3e-12) amino acids 342 to 376 (35 residues), 29.5 bits, see alignment (E = 5.7e-11) amino acids 352 to 385 (34 residues), 25.1 bits, see alignment (E = 1.4e-09) amino acids 378 to 412 (35 residues), 31.5 bits, see alignment (E = 1.4e-11) amino acids 414 to 448 (35 residues), 35.4 bits, see alignment (E = 8.4e-13) amino acids 440 to 475 (36 residues), 30.3 bits, see alignment (E = 3.3e-11) amino acids 450 to 484 (35 residues), 31.1 bits, see alignment (E = 1.8e-11) amino acids 467 to 502 (36 residues), 28.4 bits, see alignment (E = 1.3e-10) amino acids 504 to 538 (35 residues), 34.4 bits, see alignment (E = 1.7e-12) amino acids 530 to 555 (26 residues), 22.5 bits, see alignment (E = 9.2e-09) amino acids 636 to 662 (27 residues), 13.5 bits, see alignment (E = 6e-06) PF13403: Hint_2" amino acids 753 to 899 (147 residues), 129.1 bits, see alignment E=1.8e-41

Best Hits

Predicted SEED Role

"Type I secretion target repeat protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See I7DUF2 at UniProt or InterPro

Protein Sequence (959 amino acids)

>PGA1_c30600 RTX toxins and related Ca2+-binding proteins (Phaeobacter inhibens DSM 17395)
MPRQSWLEDLLATLIGGKGKDKMGGTKGDDTMDAGEGDDTVAGEEGDDIISAGDGDDIVY
GDMGDGFDQGVQASPLTLDINNMRSVSHDGGTGSAGNYAVFSNVATLEDGTSISGKLILV
EKSNANMSVTFGYDAGAEILLDGDQSGDQAKFRLEFFDPATGDAVFLDSTATFNDIDDNS
YSGDAEAVIIDGNSFTSFGVSSDSSLTTDVNGNVVKATGSELNDYTDQDSWFSASFEDRS
SIEFTLQTRAGLAGFTLSGDVLDDPVTTIIEQGDDTVMGGEGNDVVYGQGGNDSLLGEEG
DDSLDGGDGDDVIEGGVGADTLMGGSGGDTLSGGDGDDYIEGGEGDDQLSTGIGNDTLLG
GEGNDTLNNSAGDDSLVGGVGNDSIVATDGFDTLEGGDGDDTMYGGNDDDLLLGGADNDL
MYGETGNDSLDGGDGNDVMDGGVGNDTLMGGLGADTIAGGDGDDYIDGGDGDDSLTTGLG
NDTLIGGAGNDTLRNSAGDDSLVGGTGDDSIVATDGNDTLEGGDGADTMYGGNDDDLLVG
GAGDDKMYGEADADTFQMSDGFGNDTISGGEAGNDSDHIDMSNVTSSVSVTYSGFEAGQI
TDGADTISFSEIEQLTLTDQADVVDASADNAGVNIDAGAGDDTITFGEGDDSITGGAGDD
DLLLTEGGGVDTVSDFDLNDDDGNGFYNDQLDVSDLAGGSGTGGAVRTGDVAVADDGFGN
ALLTFPGGEQLVLQGVTPAQMSSHNQLYAAGIPCFTPDVQLATRRGAVPAGQIRVGDLLQ
TADNGFQPVIWVGKRSLSVADLEKRPQLRPYCLRPGGVLSPDRPMLLSPQHRLIVNDRCL
MPEQPRDESFVSAKLLAEMDEDFVAQVMHRAPVTYVHLMTEQHEVIFAEGIATETFWPGP
EAIRGLSADDLRELLTLFPELATVHGLSGEPGRRQVRKTYGDLARRSLRRRDIADRHAA