Protein Info for PGA1_c30010 in Phaeobacter inhibens DSM 17395

Annotation: haloacid dehalogenase-like protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 237 PF00702: Hydrolase" amino acids 7 to 194 (188 residues), 46 bits, see alignment E=4.2e-16

Best Hits

KEGG orthology group: K07025, putative hydrolase of the HAD superfamily (inferred from 73% identity to sit:TM1040_2535)

Predicted SEED Role

"Hydrolase, haloacid delahogenase-like family"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See I7DUA1 at UniProt or InterPro

Protein Sequence (237 amino acids)

>PGA1_c30010 haloacid dehalogenase-like protein (Phaeobacter inhibens DSM 17395)
MTRKLTTIGFDADDTLWHNERFFRITQDRFAELLMDHVPQEFDSQALGDRLLAAEKQNLG
RYGYGVKGFTLSMIETAIEVTDARVPASVIQELIVAGQMMLSYPIELLPNAQSAVEALAD
SHRVVLVTKGDLLDQERKLAQSGLGDLFDGVEIVSEKTPQIYAEIFARHGDGPEHAMMVG
NSMRSDVVPIIEAGGWGTYVPHGLVWGVEYAPAPVQSPRYTEIADLSALPTLVARIS