Protein Info for HP15_2880 in Marinobacter adhaerens HP15

Annotation: urea ABC transporter, permease protein UrtB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 532 signal peptide" amino acids 1 to 25 (25 residues), see Phobius details transmembrane" amino acids 243 to 266 (24 residues), see Phobius details amino acids 274 to 292 (19 residues), see Phobius details amino acids 298 to 318 (21 residues), see Phobius details amino acids 330 to 348 (19 residues), see Phobius details amino acids 382 to 399 (18 residues), see Phobius details amino acids 428 to 449 (22 residues), see Phobius details amino acids 463 to 486 (24 residues), see Phobius details amino acids 497 to 515 (19 residues), see Phobius details TIGR03409: urea ABC transporter, permease protein UrtB" amino acids 241 to 528 (288 residues), 417.5 bits, see alignment E=1.8e-129 PF02653: BPD_transp_2" amino acids 245 to 513 (269 residues), 158.2 bits, see alignment E=1.2e-50

Best Hits

KEGG orthology group: K01997, branched-chain amino acid transport system permease protein (inferred from 73% identity to maq:Maqu_3000)

Predicted SEED Role

"Urea ABC transporter, permease protein UrtB" in subsystem Urea decomposition

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See E4PMD2 at UniProt or InterPro

Protein Sequence (532 amino acids)

>HP15_2880 urea ABC transporter, permease protein UrtB (Marinobacter adhaerens HP15)
MSICRSLTLLLIALLSLLSLPATAQEEDPGKALLINLAEAPASKVEEAVNAIVSSGDERA
RGWLEAYGNNRLSRVKDTGQVVLVLNNRGRDWEIADPLTGENMGEMSRRELDRVAINNRI
RGQLEGILAMLDLNAKDPDVREASAQDMMGKVDASLVEPLEAQLAKEEDAAVRNRIEEAL
AIYRVGEGNLEAVDVLAGSLHPRARAALNEAVRGDNEALAQRAAKALESIEQKLQLNRAA
ETLYFGLSLGSVLVLAAIGLAITFGVMGVINMAHGELIMLGAYTTWGMQQLFPGQPGLAL
ILSIPAGFLVAATAGIIIERSVIQYLKGRPLETLLATFGISLILQQLVRTVISPQNRTVV
TPDWMSGSLVINDALSLTLNRLYVLAFALIVFAGLMLIMRKTRLGLEVRAVTQNRAMARS
MGIRATRVDIMTFALGSGVAGLAGVALSQLTNVGPNLGQNYIIDSFMVVVFGGVGNLWGT
LIAGLSLGTINQLLEPWAGAVLAKIIVLVFIILFIQKRPKGLFPQKGRAAEG