Protein Info for PGA1_c29770 in Phaeobacter inhibens DSM 17395

Annotation: putative mechanosensitive ion channel

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 453 transmembrane" amino acids 47 to 72 (26 residues), see Phobius details amino acids 93 to 113 (21 residues), see Phobius details amino acids 120 to 142 (23 residues), see Phobius details amino acids 154 to 173 (20 residues), see Phobius details amino acids 185 to 207 (23 residues), see Phobius details amino acids 228 to 250 (23 residues), see Phobius details amino acids 256 to 285 (30 residues), see Phobius details PF00924: MS_channel_2nd" amino acids 274 to 340 (67 residues), 63.6 bits, see alignment E=1.5e-21 PF21082: MS_channel_3rd" amino acids 348 to 433 (86 residues), 30.5 bits, see alignment E=4.1e-11

Best Hits

KEGG orthology group: None (inferred from 65% identity to jan:Jann_0136)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See I7EQN3 at UniProt or InterPro

Protein Sequence (453 amino acids)

>PGA1_c29770 putative mechanosensitive ion channel (Phaeobacter inhibens DSM 17395)
MNPDEQIETKDALAESTAEAIELGQQLWDFLTNTAEVLLRPWNAYQLGIAAGLLVLAAVL
AKPIAGAFHDWLRGRTGWPRWRMRAGLVLHKRIRGILFVLLIWTTVLIMQDITWPSRSRL
LVVIANLSLAWLIVSFATRLVANPLLRKLVKYGAWTWVTLRILGITAEATAFLDSVAIDF
GDLRISLFLIVQAVVILGVMLTLARAISSVAANRIRNNPDISPSMQVLGAKLAQILLLGG
AFFIGLKAIGIDLTGLAVLSGAIGVGLGFGLQKVVSNLVSGLIILLDKSIKPGDVISLGE
TFGWINSLGARYVSVVTRDGREYLIPNEDFITNEVVNWSHTDRFVRLDLNFGTGYSDDPH
EVRRVAIEAAKTVGRVLSGGNRAPVCHIVGFGDSSVDYVLRFWISDPTGGLTNIRGNVYL
ALWDAFKGAGISIPFPQREVRVLNEALPVAMQD