Protein Info for Psest_2979 in Pseudomonas stutzeri RCH2

Annotation: sodium ion-translocating decarboxylase, beta subunit

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 378 transmembrane" amino acids 14 to 35 (22 residues), see Phobius details amino acids 42 to 60 (19 residues), see Phobius details amino acids 74 to 93 (20 residues), see Phobius details amino acids 105 to 129 (25 residues), see Phobius details amino acids 165 to 187 (23 residues), see Phobius details amino acids 213 to 239 (27 residues), see Phobius details amino acids 259 to 278 (20 residues), see Phobius details amino acids 287 to 308 (22 residues), see Phobius details amino acids 355 to 377 (23 residues), see Phobius details TIGR01109: sodium ion-translocating decarboxylase, beta subunit" amino acids 19 to 372 (354 residues), 564.5 bits, see alignment E=4.4e-174 PF03977: OAD_beta" amino acids 20 to 376 (357 residues), 530.2 bits, see alignment E=1.2e-163

Best Hits

KEGG orthology group: K01572, oxaloacetate decarboxylase, beta subunit [EC: 4.1.1.3] (inferred from 96% identity to psa:PST_1378)

Predicted SEED Role

"Oxaloacetate decarboxylase beta chain (EC 4.1.1.3)" in subsystem Na+ translocating decarboxylases and related biotin-dependent enzymes or Pyruvate metabolism I: anaplerotic reactions, PEP (EC 4.1.1.3)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 4.1.1.3

Use Curated BLAST to search for 4.1.1.3

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0GND4 at UniProt or InterPro

Protein Sequence (378 amino acids)

>Psest_2979 sodium ion-translocating decarboxylase, beta subunit (Pseudomonas stutzeri RCH2)
MDKLLKLWQGTGLYHLEPGQALMILVCLGLIYLAIRKGFEPLLLIPIGFGGILANIPVAN
MGEGAGILHLFYEVGLPTSVFPLLIFMGVGAMTDFGPMLANPKTLLLGAAAQFGIFATLL
GALALTAAGIPGMEFTLREAASIAIIGGADGPTSIFVTSKLAPELLGPIAVAAYSYMALV
PLIQPPIMRALTTKEERAIVMTQLRHVSQVEKIVFPLVLCLLVGLLLPDAAPLVGMFAFG
NLLRECGVVDRLADTSRNALINIVTIALGLTVGSKLSAEAFLQIKTLGILVLGMVAFCGG
TAAGIFMAKIMNRFSQNKINPLIGSAGVSAVPMAARVSNKVGLEANPQNFLLMHAMGPNV
AGVIGSAVAAGVLLNFVG