Protein Info for PGA1_c29250 in Phaeobacter inhibens DSM 17395

Annotation: putative haloacid dehalogenase-like hydrolase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 222 PF00702: Hydrolase" amino acids 9 to 185 (177 residues), 80.4 bits, see alignment E=2.5e-26 PF13419: HAD_2" amino acids 11 to 190 (180 residues), 81.3 bits, see alignment E=9.9e-27 TIGR01509: HAD hydrolase, family IA, variant 3" amino acids 50 to 190 (141 residues), 46.7 bits, see alignment E=4e-16

Best Hits

KEGG orthology group: None (inferred from 63% identity to sil:SPO3762)

Predicted SEED Role

"Putative phosphatase YieH" in subsystem 2-phosphoglycolate salvage

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See I7F051 at UniProt or InterPro

Protein Sequence (222 amino acids)

>PGA1_c29250 putative haloacid dehalogenase-like hydrolase (Phaeobacter inhibens DSM 17395)
MPITYPTPKLVIFDCDGVLVDSETLSNQVLVENLGRHGLQLSLADCMDLFVGGTMQGVMK
KAQELGADLPANWVDEVYGETYARLRQGVDLVPGIPDLLALLQARGIAFCVASNGSEDKM
RITLGQNGLWDQFHPQAMFSAHTLKTGKPDPDLFLAAACHFDVQARDCLVIEDSENGAIA
AARAGMRCLGFDPHGKGTRLKRHNAEHITAMSEVPRLIGLRP