Protein Info for HP15_2774 in Marinobacter adhaerens HP15

Annotation: DSBA oxidoreductase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 215 PF01323: DSBA" amino acids 6 to 207 (202 residues), 137.9 bits, see alignment E=3.7e-44 PF13462: Thioredoxin_4" amino acids 114 to 206 (93 residues), 25.3 bits, see alignment E=1.6e-09

Best Hits

KEGG orthology group: None (inferred from 41% identity to psm:PSM_B0382)

Predicted SEED Role

"2-hydroxychromene-2-carboxylate isomerase/DsbA-like thioredoxin domain"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See E4PLE7 at UniProt or InterPro

Protein Sequence (215 amino acids)

>HP15_2774 DSBA oxidoreductase (Marinobacter adhaerens HP15)
MKTISIDIVSDIACPWCAIGYARLEQAMKQLASEYEFGLQWHAFELNPDHSGTGEPILPA
LARKYGRSEQEMRATQDQMMTIAKDLGLNFEKMQERFTCNTFDAHRLVKWAAEQGKQTEM
KQALFEAYFGKAEDVSDQDVLLACVESLGLDRGRAKQILDSDEFANVVREDEATYQQAGV
SAVPAFIVNGKYLISGAQEPDTLVQAFEEISAKPE