Protein Info for HP15_2740 in Marinobacter adhaerens HP15

Annotation: membrane protein containing DUF6, transmembrane

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 298 transmembrane" amino acids 12 to 31 (20 residues), see Phobius details amino acids 44 to 62 (19 residues), see Phobius details amino acids 74 to 95 (22 residues), see Phobius details amino acids 101 to 122 (22 residues), see Phobius details amino acids 129 to 147 (19 residues), see Phobius details amino acids 155 to 175 (21 residues), see Phobius details amino acids 187 to 209 (23 residues), see Phobius details amino acids 219 to 239 (21 residues), see Phobius details amino acids 251 to 269 (19 residues), see Phobius details amino acids 275 to 293 (19 residues), see Phobius details PF00892: EamA" amino acids 19 to 145 (127 residues), 50.4 bits, see alignment E=1.3e-17 amino acids 158 to 293 (136 residues), 45.9 bits, see alignment E=3.3e-16

Best Hits

KEGG orthology group: None (inferred from 84% identity to maq:Maqu_2933)

Predicted SEED Role

"Permease of the drug/metabolite transporter (DMT) superfamily" in subsystem Queuosine-Archaeosine Biosynthesis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See E4PKM8 at UniProt or InterPro

Protein Sequence (298 amino acids)

>HP15_2740 membrane protein containing DUF6, transmembrane (Marinobacter adhaerens HP15)
MFPIATGINAMPISVHYGLTVLIWGLTWTAIRLQVEAAPVDLSVFYRFVMASAVALLVVA
LVRRLEKLTLKQHGWLVLQGATLYSINFLLIYRAAESMTSGLLAVVFSLAALFNALNGWL
WLRLRPTARLYPAISLGITGVALLFWHDLQLGNATATSILFAIAGTFWFSMGNLVSIKVR
MSKVPLFLANAWAMVYGAVILGIWCLIQGVEWVVPTAATFWGATVFLAVPGSIIAFYCYI
TVIQTLGADKAGYATVLFPVVALSVSTWLEGFEWTATAVLGASLALLGNYVLFRSAKA