Protein Info for Psest_2849 in Pseudomonas stutzeri RCH2

Annotation: Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 499 signal peptide" amino acids 1 to 23 (23 residues), see Phobius details transmembrane" amino acids 32 to 51 (20 residues), see Phobius details amino acids 72 to 75 (4 residues), see Phobius details amino acids 77 to 97 (21 residues), see Phobius details amino acids 128 to 147 (20 residues), see Phobius details amino acids 161 to 183 (23 residues), see Phobius details amino acids 205 to 229 (25 residues), see Phobius details amino acids 241 to 264 (24 residues), see Phobius details amino acids 277 to 296 (20 residues), see Phobius details amino acids 303 to 322 (20 residues), see Phobius details amino acids 329 to 351 (23 residues), see Phobius details amino acids 372 to 391 (20 residues), see Phobius details amino acids 411 to 431 (21 residues), see Phobius details amino acids 452 to 473 (22 residues), see Phobius details PF00361: Proton_antipo_M" amino acids 126 to 411 (286 residues), 136 bits, see alignment E=8.2e-44

Best Hits

KEGG orthology group: K05561, multicomponent K+:H+ antiporter subunit D (inferred from 93% identity to psa:PST_1531)

Predicted SEED Role

"Na(+) H(+) antiporter subunit D" in subsystem Sodium Hydrogen Antiporter

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0GKR6 at UniProt or InterPro

Protein Sequence (499 amino acids)

>Psest_2849 Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit (Pseudomonas stutzeri RCH2)
MNHALILPLLVPLFVGAVLLFAHRMGKPAKRLLSLAATWALVPIALWLVLLSDDGQLRIY
ALGSWQPPFGIILMLDRLSALMLLVTAVLAGFAVLYASRGDDERGPNFHALYQFQLLGIN
GAFLTGDLFNLFVFFEILLISSYALLLHGHGQRRVRAGMHYVVLNLLGSSLFLIGVSMLY
GLLGTLNMADMAGRVSAAEPADAPLLAAAGYLLLVVFALKGAILPLYFWLPRAYASATAP
VAALFAIMTKVGLYAIVRVFTLVFGSEAGELSNMVEVWLWPLALLTLGAAVIGALAARNL
QVLLAYLVVVSVGTLLAGIALGTDVGLAAALYYLVHSTLVAGGLFLLADLIARQRGDLGT
DLVSAPALRQPLLLGSLFFMGAISVAGLPPFSGFLGKVMLLRAIDVGPDAIALWAVVLVG
GLGMLIALSRAGSLVFWRHASEAVGQVADPIRVVATAGLLLASVALVAAAGPLQAFMQAT
AAQLLDVAPYLQIVPGGAA