Protein Info for HP15_2735 in Marinobacter adhaerens HP15

Annotation: diguanylate cyclase with PAS/PAC sensor

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 312 TIGR00229: PAS domain S-box protein" amino acids 13 to 136 (124 residues), 40 bits, see alignment E=3.9e-14 PF08447: PAS_3" amino acids 38 to 123 (86 residues), 52.8 bits, see alignment E=3.9e-18 TIGR00254: diguanylate cyclase (GGDEF) domain" amino acids 143 to 310 (168 residues), 167.4 bits, see alignment E=2.3e-53 PF00990: GGDEF" amino acids 148 to 308 (161 residues), 161.3 bits, see alignment E=1.7e-51

Best Hits

KEGG orthology group: None (inferred from 70% identity to maq:Maqu_2914)

Predicted SEED Role

"FOG: PAS/PAC domain"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See E4PKM3 at UniProt or InterPro

Protein Sequence (312 amino acids)

>HP15_2735 diguanylate cyclase with PAS/PAC sensor (Marinobacter adhaerens HP15)
MSDNPAGLVEDSSVYRTLLESTRAIPWKINWRTMQFEYIGPQIEALLGWPQDSWLTVDDW
ATRMHPEDRERVVNFCVSQSEAGVDHEADYRALTEGGEYVWLRDVVHVLRDDNGDVEALI
GFMFDISERKKTEDELVALQKKLEEYSYKDGLTGVANRRMFDTVMNENWNHAIRHQSSLS
VILLDIDNFKAYNDLNGHLQGDECLKRIATLLENAAQRPRDFVARFGGEEFVIVLPETDA
SAAISVAERCRQLLLEEQIPQGDSPNSKKVTISMGIGTVVPSRDDCIADFLDLVDQRLYK
AKRDGRNRIVFD