Protein Info for Psest_2837 in Pseudomonas stutzeri RCH2

Annotation: CDP-diglyceride synthetase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 271 transmembrane" amino acids 7 to 41 (35 residues), see Phobius details amino acids 55 to 72 (18 residues), see Phobius details amino acids 78 to 96 (19 residues), see Phobius details amino acids 104 to 125 (22 residues), see Phobius details amino acids 134 to 155 (22 residues), see Phobius details amino acids 176 to 197 (22 residues), see Phobius details amino acids 203 to 222 (20 residues), see Phobius details amino acids 251 to 270 (20 residues), see Phobius details PF01148: CTP_transf_1" amino acids 3 to 265 (263 residues), 229.5 bits, see alignment E=3.4e-72

Best Hits

Swiss-Prot: 73% identical to CDSA_PSEAE: Phosphatidate cytidylyltransferase (cdsA) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)

KEGG orthology group: K00981, phosphatidate cytidylyltransferase [EC: 2.7.7.41] (inferred from 74% identity to pfv:Psefu_3427)

Predicted SEED Role

"Phosphatidate cytidylyltransferase (EC 2.7.7.41)" in subsystem Glycerolipid and Glycerophospholipid Metabolism in Bacteria (EC 2.7.7.41)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.7.7.41

Use Curated BLAST to search for 2.7.7.41

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0GNG0 at UniProt or InterPro

Protein Sequence (271 amino acids)

>Psest_2837 CDP-diglyceride synthetase (Pseudomonas stutzeri RCH2)
MLKQRIITAAILLPVAIIGFFFLHGLAFALFIGLVVALGAWEWARLAGFASQPARVGYAA
LVVALLVALYQLPGLTPWLLALAIFWWLAATYLVLTYPESSRLWGGPVGSLLIGLAILLP
AWQALVVLKQWSLGNWLILAVMVLVWVADIGAYFSGKAFGKRKLAPQVSPGKSWEGLVGG
LLTSLVVTLAVGVYRGWAPRELILALLGAAVVVLISVIGDLTESMFKRSSGIKDSSQLLP
GHGGVMDRIDSLTAAVPVFAVLLWLAGWGAL