Protein Info for Psest_2717 in Pseudomonas stutzeri RCH2

Annotation: Succinylglutamate desuccinylase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF24827: AstE_AspA_cat
  • amino acids 49 to 235 (187 residues), 138.6 bits, E=1.9e-44
• PF04952: AstE_AspA_hybrid
  • amino acids 256 to 324 (69 residues), 58.4 bits, E=5.8e-20

Best Hits

Swiss-Prot: 54% identical to ASTE_PSEA7: Succinylglutamate desuccinylase (astE) from Pseudomonas aeruginosa (strain PA7)

KEGG orthology group: K05526, succinylglutamate desuccinylase [EC: 3.5.1.96] (inferred from 78% identity to psa:PST_1651)

Predicted SEED Role

"Succinylglutamate desuccinylase (EC 3.5.1.96)" in subsystem Arginine and Ornithine Degradation (EC 3.5.1.96)

MetaCyc Pathways

• L-arginine degradation II (AST pathway) (2/5 steps found)

KEGG Metabolic Maps

• Arginine and proline metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.5.1.96

Sequence Analysis Tools

See L0GPB9 at UniProt or InterPro

Protein Sequence (332 amino acids)

>Psest_2717 Succinylglutamate desuccinylase (Pseudomonas stutzeri RCH2)
MLALGKLLELTLAGREPCEKVQLTPRGVKLHWLADGALLVSPPPGQDQGLDLLLSAGIHG
NELIPIHVLDRLVRALARDDVRPRAPLLLLFANPAAMRRMVRQVEHDLNRLFRGEHADVW
GGEAIRAAELEALVGGFFSGAGRQRRHYDLHSALRPSRLAQFAICPWRECEQVSAESLTR
LDRLAIEGVLLQRQATSTFSAMTSTRYGAEAFTLELAEGAGESLPVAVVQFERGLYGMIE
GREAPVAAHALPQLLQISREVIKRSPRFRLCVPSDIENFAPLPLGSVLAEDDGARWVIDE
PGARILFPMADVAEGQRAALIVVPLEQTEGER