Protein Info for PGA1_c26760 in Phaeobacter inhibens DSM 17395

Annotation: virulence factor MviN

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 518 signal peptide" amino acids 1 to 20 (20 residues), see Phobius details transmembrane" amino acids 29 to 49 (21 residues), see Phobius details amino acids 91 to 113 (23 residues), see Phobius details amino acids 131 to 151 (21 residues), see Phobius details amino acids 159 to 182 (24 residues), see Phobius details amino acids 188 to 208 (21 residues), see Phobius details amino acids 229 to 249 (21 residues), see Phobius details amino acids 270 to 290 (21 residues), see Phobius details amino acids 312 to 335 (24 residues), see Phobius details amino acids 347 to 369 (23 residues), see Phobius details amino acids 382 to 400 (19 residues), see Phobius details amino acids 406 to 427 (22 residues), see Phobius details amino acids 448 to 471 (24 residues), see Phobius details amino acids 477 to 501 (25 residues), see Phobius details TIGR01695: murein biosynthesis integral membrane protein MurJ" amino acids 6 to 493 (488 residues), 367.2 bits, see alignment E=7e-114 PF03023: MurJ" amino acids 32 to 466 (435 residues), 316 bits, see alignment E=1.8e-98

Best Hits

Swiss-Prot: 46% identical to MURJ_RHIME: Probable lipid II flippase MurJ (murJ) from Rhizobium meliloti (strain 1021)

KEGG orthology group: K03980, virulence factor (inferred from 78% identity to sil:SPO0396)

Predicted SEED Role

"Proposed peptidoglycan lipid II flippase MurJ" in subsystem ZZ gjo need homes

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See I7E3M3 at UniProt or InterPro

Protein Sequence (518 amino acids)

>PGA1_c26760 virulence factor MviN (Phaeobacter inhibens DSM 17395)
MKPIKLLSGFLTVGFWTLASRILGFLREILITAYIGPGPLMDAFVAAFRLPNMFRRFFAE
GAFNAAFVPMFAKRLESGEDPQGFAQEAFNLLAITVLLLVGLGMVFMPALVWATAGGFVG
DARFDLAVGYGQIVFPYILCMSLAALFSGVLNATGRFAAAAAAPVLLNIFACAAMVAGAV
LGGEVISWLVWTIPVAGVAQLALVWIAASRTGIRLRPGLPRWTPQMKNLVRVALPAALAM
GVTQINLVVGQQVASDIENAVSWLFVADRLYQLPLGVVGIAIGIVLLPDLSRRLRAGDDA
GARDAFSRAGEFSLLLTLPSTAAFLAVPLVLVSVLYERGATGADDVAAIALAVAVYGAGL
PAFVLQKVLQPLFFAREDTRSPFRYAVVAMVINAVLAFGLKPYLGWIAPAIAATVAGWTM
VACLWLGARRMGEVARFDQRFYDRSLRILTASAIMGAVLFGLVQQFGWLFYLPSWRYLAL
LGLIVLGAVVYFGVGQIIGAVRLGDIKRAVRRGGTPTQ