Protein Info for HP15_2559 in Marinobacter adhaerens HP15

Annotation: membrane protein containing DUF6, transmembrane

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 301 transmembrane" amino acids 7 to 25 (19 residues), see Phobius details amino acids 34 to 55 (22 residues), see Phobius details amino acids 74 to 92 (19 residues), see Phobius details amino acids 104 to 120 (17 residues), see Phobius details amino acids 128 to 150 (23 residues), see Phobius details amino acids 156 to 174 (19 residues), see Phobius details amino acids 185 to 205 (21 residues), see Phobius details amino acids 215 to 236 (22 residues), see Phobius details amino acids 246 to 265 (20 residues), see Phobius details amino acids 270 to 286 (17 residues), see Phobius details PF00892: EamA" amino acids 7 to 142 (136 residues), 62.7 bits, see alignment E=2.3e-21 amino acids 156 to 286 (131 residues), 73.5 bits, see alignment E=1.1e-24

Best Hits

KEGG orthology group: K07052, (no description) (inferred from 84% identity to maq:Maqu_2825)

Predicted SEED Role

"Permease of the drug/metabolite transporter (DMT) superfamily" in subsystem Queuosine-Archaeosine Biosynthesis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See E4PIS2 at UniProt or InterPro

Protein Sequence (301 amino acids)

>HP15_2559 membrane protein containing DUF6, transmembrane (Marinobacter adhaerens HP15)
MTNQKQAMLYGLGTVLLWSTVATAFKLSLRELAPVQMLLIACSASVVVMAVILMLQGRWH
LVFSLSRKQYAQSFGMGLINPCLYYFLLFGAFDRLPAQEAQPLNYTWALVLAYMSVPFLG
HRLRKLDIVAGLICYAGVVVIATRGAVTSLSFEDPLGVSLALGSTVVWASYWIIATRDTR
DPVVGLFLNFLCGLPVILLICWWTEGLSFAPGTSLAAALYVGVFEMGIAFVLWSYAMKKA
ENTSKVSNLIFISPFLSLVFIYFILGEHILPSTYIGLVLIMMGLWIQQKKVKDREEALNL
G