Protein Info for HP15_2522 in Marinobacter adhaerens HP15

Annotation: methyl-accepting chemotaxis sensory transducer

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 545 transmembrane" amino acids 12 to 33 (22 residues), see Phobius details amino acids 193 to 217 (25 residues), see Phobius details PF12729: 4HB_MCP_1" amino acids 9 to 169 (161 residues), 30 bits, see alignment E=5.7e-11 PF00672: HAMP" amino acids 213 to 264 (52 residues), 38 bits, see alignment 2.6e-13 PF00015: MCPsignal" amino acids 346 to 511 (166 residues), 151.6 bits, see alignment E=3e-48

Best Hits

KEGG orthology group: K03406, methyl-accepting chemotaxis protein (inferred from 77% identity to maq:Maqu_2789)

Predicted SEED Role

"Methyl-accepting chemotaxis protein I (serine chemoreceptor protein)" in subsystem Bacterial Chemotaxis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See E4PIN5 at UniProt or InterPro

Protein Sequence (545 amino acids)

>HP15_2522 methyl-accepting chemotaxis sensory transducer (Marinobacter adhaerens HP15)
MDFGKRLGLRVKIALPFVITAVALVVIGLFAVSTVRNLVSDTDNIADTYLPSVSEILNGD
RDLYQALVAQMAYVDAQSNDEDGENYLASFDENAGQALDRFKTAVGRLEGTGVSDVARGF
DAAYERWLGSAQRVLELAETGDPEQARALAASETNNLFDNLRNYFDEVGAHADARAQIRA
GEASSEGQSSSVTILLITAVAILISIGLFAVFLKLIISSIAALRDQLDNIAQGEGDLTQR
IPVEMDDDLGKLAKSFNLVLENLQSMIGSIQQLTRELGTGATDLARAAKDNNDGVTRQTD
SISMVATAINEMQSAIEEVAGNASRAAEITRDAEEKGKNGARIIRNSSEQVHRLAAQISK
AVEVIRKLSDDSDNITSVLDVIRGIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRTL
AQRTGQSTEDIQKMITTLQAGVADIVSVMETGSKEASETEKLATDAESELKAILEAMANI
ADVNTSVASATEEQTQVVDEINRSITEINDLATESASRSRDIDGISESLEGYARELESQT
GRFRV