Protein Info for Psest_2564 in Pseudomonas stutzeri RCH2

Annotation: NAD(P)H:quinone oxidoreductase, type IV

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 208 transmembrane" amino acids 125 to 144 (20 residues), see Phobius details TIGR01755: NAD(P)H:quinone oxidoreductase, type IV" amino acids 2 to 198 (197 residues), 309.8 bits, see alignment E=4.7e-97 PF03358: FMN_red" amino acids 3 to 142 (140 residues), 60 bits, see alignment E=4.1e-20 PF02525: Flavodoxin_2" amino acids 3 to 137 (135 residues), 27.4 bits, see alignment E=5.4e-10 PF00258: Flavodoxin_1" amino acids 6 to 124 (119 residues), 36.8 bits, see alignment E=8.4e-13

Best Hits

Swiss-Prot: 80% identical to NQOR_PARDP: NAD(P)H dehydrogenase (quinone) (Pden_4564) from Paracoccus denitrificans (strain Pd 1222)

KEGG orthology group: K03809, Trp repressor binding protein (inferred from 88% identity to psa:PST_1801)

MetaCyc: 58% identical to PnpB (Pseudomonas sp. WBC-3)
2-hydroxy-1,4-benzoquinone reductase. [EC: 1.6.5.7]; p-benzoquinone reductase (NADPH). [EC: 1.6.5.7, 1.6.5.6]

Predicted SEED Role

"Trp repressor binding protein"

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.6.5.6 or 1.6.5.7

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0GM70 at UniProt or InterPro

Protein Sequence (208 amino acids)

>Psest_2564 NAD(P)H:quinone oxidoreductase, type IV (Pseudomonas stutzeri RCH2)
MTKVLVLYYSSYGHIEALAQAVAEGAREVGALADIKRVPELVPEQVAHKAGYKMSQSAGV
ASVSELPDYDAIVIGTPTRFGNMASQMKNFLDQCGGLWAEDRLVGKVGSVFTSTGSQHGG
QESTILATHTVLLHFGMVVVGLPYSFKGQLRMDAVTGGSPYGASTLSDDGSGGDRQPSEN
ELEGARYQGAHVARIAAALATHSFGTPR