Protein Info for PGA1_c25350 in Phaeobacter inhibens DSM 17395

Annotation: putative transcriptional regulator, TetR family

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 203 PF00440: TetR_N" amino acids 13 to 58 (46 residues), 43 bits, see alignment 3.2e-15 PF13305: TetR_C_33" amino acids 85 to 180 (96 residues), 40.9 bits, see alignment E=2.8e-14

Best Hits

Predicted SEED Role

"regulatory protein, TetR"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See I7EPL0 at UniProt or InterPro

Protein Sequence (203 amino acids)

>PGA1_c25350 putative transcriptional regulator, TetR family (Phaeobacter inhibens DSM 17395)
MKTASTDNPRSGITKAARHLLERGGISALSMRSIAKHLGVSAMMPYKHFPSKDHILMELR
LEAFQRLTTHMRRAQAVAQTPTDALVAVSQAYVGFALKAPNDYRLMFDAWEFENYAQIAA
DFGDSISREADSWHVNLDAVTAFAEAENLAIDCNFAAHWLWSSLHGMVQLHLSRKLAFGM
EIQPLGQIFSEKIPTSIRAFSQK