Protein Info for Psest_0025 in Pseudomonas stutzeri RCH2

Annotation: DNA protecting protein DprA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 365 TIGR00732: DNA protecting protein DprA" amino acids 74 to 292 (219 residues), 263.7 bits, see alignment E=4.8e-83 PF02481: DNA_processg_A" amino acids 79 to 283 (205 residues), 255.1 bits, see alignment E=3.9e-80

Best Hits

KEGG orthology group: K04096, DNA processing protein (inferred from 87% identity to psa:PST_0023)

Predicted SEED Role

"Rossmann fold nucleotide-binding protein Smf possibly involved in DNA uptake" in subsystem Conserved gene cluster associated with Met-tRNA formyltransferase

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0GD44 at UniProt or InterPro

Protein Sequence (365 amino acids)

>Psest_0025 DNA protecting protein DprA (Pseudomonas stutzeri RCH2)
MPAISPAELEARLRLHLLPELGPRRLRKLVSAFPDAASALSAPASAWRSLGLPASCAEPR
RSAEIRERASAALAWLEQPERHLLCWDDPNYPALLAELPDAPPLLFIAGDPSLLERPQLA
MVGSRRASRNGLDNARAFSRSLAGAGFIITSGLALGIDGAAHQGALDAGGKTIAVLGTGI
ERLYPQRHVALARQIVEGGGALVSELPLDCPPQASNFPRRNRIISGLSLGVLVVEASPSS
GSLITARLAAEQGREVYAIPGSIHHPGARGCHQLIRQGAALVESVEDVLEALRGWQCVAP
AAGETRTQTRPDNPLLRELLAAPRSSEALAVALDQPLGQVLAQLTELEVDGLVASDNGLW
VVISR