Protein Info for PGA1_c25090 in Phaeobacter inhibens DSM 17395

Annotation: ATP synthase subunit beta

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 474 TIGR01039: ATP synthase F1, beta subunit" amino acids 5 to 469 (465 residues), 836 bits, see alignment E=4.1e-256 PF02874: ATP-synt_ab_N" amino acids 8 to 73 (66 residues), 70.8 bits, see alignment E=1.7e-23 PF00006: ATP-synt_ab" amino acids 131 to 351 (221 residues), 228.5 bits, see alignment E=1.1e-71 PF22919: ATP-synt_VA_C" amino acids 358 to 446 (89 residues), 66.1 bits, see alignment E=3.8e-22

Best Hits

Swiss-Prot: 96% identical to ATPB_RUEST: ATP synthase subunit beta (atpD) from Ruegeria sp. (strain TM1040)

KEGG orthology group: K02112, F-type H+-transporting ATPase subunit beta [EC: 3.6.3.14] (inferred from 96% identity to sit:TM1040_2086)

MetaCyc: 78% identical to ATP synthase subunit beta, mitochondrial (Homo sapiens)

Predicted SEED Role

"ATP synthase beta chain (EC 3.6.3.14)" in subsystem F0F1-type ATP synthase (EC 3.6.3.14)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.6.3.14

Use Curated BLAST to search for 3.6.3.14

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See I7EPH8 at UniProt or InterPro

Protein Sequence (474 amino acids)

>PGA1_c25090 ATP synthase subunit beta (Phaeobacter inhibens DSM 17395)
MANAKGKVTQIIGAVVDVQFDGHLPAILNALTTDNNGKTLVLEVAQHLGENTVRTIAMDA
TEGLVRGQAVADTDAPISIPVGNATLGRILNVVGEPVDEQGPVVAAETRAIHQPAPEFSD
QSTESEVLVTGIKVIDLLAPYAKGGKIGLFGGAGVGKTVLIMELINNIAKVHSGFSVFAG
VGERTREGNDLYHEMIESNVIKPDNLEESQVALVYGQMNEPPGARARVALTGLTLAEQFR
DQSGTDVLFFVDNIFRFTQAGSEVSALLGRIPSAVGYQPTLATDMGAMQERITSTKNGSI
TSIQAVYVPADDLTDPAPATTFAHLDATTVLNRSISELGIYPAVDPLDSTSRLMDPSIVG
EEHYAVASDVQQILQRYKSLQDIIAILGMDELSEEDKLTVTRARKIQRFLSQPFDVAKVF
TGADGKQVPLEDTIKSFKAVVAGEYDHLPEGAFYMVGGIDEVIAKAEKMAADAA