Protein Info for Psest_2478 in Pseudomonas stutzeri RCH2

Annotation: Na+/serine symporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 408 signal peptide" amino acids 1 to 39 (39 residues), see Phobius details transmembrane" amino acids 48 to 70 (23 residues), see Phobius details amino acids 82 to 104 (23 residues), see Phobius details amino acids 141 to 161 (21 residues), see Phobius details amino acids 181 to 202 (22 residues), see Phobius details amino acids 213 to 237 (25 residues), see Phobius details amino acids 289 to 313 (25 residues), see Phobius details amino acids 323 to 351 (29 residues), see Phobius details amino acids 356 to 377 (22 residues), see Phobius details PF00375: SDF" amino acids 16 to 395 (380 residues), 214.1 bits, see alignment E=1.7e-67

Best Hits

Swiss-Prot: 95% identical to SSTT_PSEU5: Serine/threonine transporter SstT (sstT) from Pseudomonas stutzeri (strain A1501)

KEGG orthology group: K07862, serine/threonine transporter (inferred from 95% identity to psa:PST_1891)

MetaCyc: 68% identical to serine/threonine:Na+ symporter (Escherichia coli K-12 substr. MG1655)
RXN-22449; RXN0-4083

Predicted SEED Role

"Sodium/dicarboxylate symporter"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0GNS3 at UniProt or InterPro

Protein Sequence (408 amino acids)

>Psest_2478 Na+/serine symporter (Pseudomonas stutzeri RCH2)
MSDMPRVIRFISRTSLVAQIVVGLVAGALLALFLPAAAKSVALLGDLFVQALKAVAPILV
FVLVTSSLANHKRGQPTHIRPIILLYALGTLSASAVAVLASFMFPTTLTLVSGAADVTPP
SGVGAVLQTLLFNVADNPVRALLNGNFIGILAWAIGLGFAFRHAQDSTRRLIGDLSDGVT
LIVKVVIRFAPLGVFGLVAGTLADSGFDVLLGYLRLLLVLVGAMLFMALVMNPLIVFWQI
RRNPYPLVFTCLRESGITAFFTRSSAANIPVNMQLCQRLGLHKDTYSVSIPLGATINMGG
AAITITVLTLAAVNTLGIQVDIATAVLLSLLAAVCACGASGVAGGSLLLIPLACSLFGIS
NDLAMQVVAVGFIIGVVQDSAETALNSSTDVLFTAASCIAHGDIAEAA